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首页> 外文期刊>Dental Materials Journal >Influence of mucin pre-adsorption for lipoteichoic acid adsorption on titanium surfaces
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Influence of mucin pre-adsorption for lipoteichoic acid adsorption on titanium surfaces

机译:粘蛋白预热对钛表面对脂素酸吸附的影响

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摘要

We investigated the adsorption of lipoteichoic acid (LTA) on titanium surfaces by using the quartz crystal microbalance (QCM) method, and confirmed the influence of mucin (MUC) pre-adsorption on LTA adsorption. Two injection methods were evaluated. Namely, Method A: single-step injection of LTA solution to the Ti sensor, and Method B: MUC solution was injected to the Ti sensor followed by LTA injection on the MUC pre-adsorbed surface. QCM measurement revealed that the adsorbed amount of LTA by Method A was low and constant regardless of the increase in LTA concentration. In contrast, the adsorption amount of LTA in Method B increased according with increasing concentration of LTA and was significantly higher than that of Method A. The hydrophobic surface after MUC pre-adsorption was presumed to contribute to the enhancement of LTA adsorption. Our results revealed that MUC pre-adsorption to Ti is necessary for LTA adsorption in living tissue.
机译:我们通过使用石英晶体微稳定(QCM)方法研究了钛酸(LTA)对钛表面的吸附,并确认了粘蛋白(MUC)预热对LTA吸附的影响。评估了两种注射方法。即,方法A:将LTA溶液的单步注射到Ti传感器,并将方法B:将MUC溶液注入Ti传感器,然后在MUC预吸附的表面上注射LTA注射。 QCM测量表明,无论LTA浓度的增加如何,通过方法A的LTA的吸附量低,恒定。相反,方法B中LTA的吸附量随着LTA的浓度的增加而增加,并且显着高于方法A的浓度。假定MUC预吸附后的疏水表面有助于提高LTA吸附。我们的结果表明,LTA在活组织中的LTA吸附是必要的MUC预吸附。

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