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首页> 外文期刊>Der Pharma Chemica: journal for medicinal chemistry, pharmaceutical chemistry and computational chemistry >The Effects of Amino Acids that contained in Fermented Soybeans Against Blood Glucose and Histopathologic Overview Pancreatic ?2 Cells of Mice White
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The Effects of Amino Acids that contained in Fermented Soybeans Against Blood Glucose and Histopathologic Overview Pancreatic ?2 Cells of Mice White

机译:氨基酸含有发酵大豆含有血糖和组织病理学概述胰腺α的疗效α2

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A study about to what extent of the effect of giving fitoesterogen contained in soybean flour obtained from soybeans fermented bean to the improvement of pancreatic β cells. Before the treatment, mice’s pancreas induced by alloxan compound. After the sample selection, mice that have been given treatment by providing tempeh flour with 3 variations doses are 40 mg; 55; 75; 105; 145 and 200 mg / 20 g BW. The mice were divided into 8 groups, group 1 is a group of negative control without being offered anything, group 2 is positive control, group of diabetic mice without being offered treatment, group 3, 4, 5, 6, 7 and 8 are given group tempeh flour with 6 dose variation. As the parameters of this study was to measure the blood glucose levels of mice on day 7th of observation; 14th and 21st. The methods used enzymatic method by using "Gluco DR". Group of mice that given tempeh flour, observed dose that can provide a decrease in blood glucose levels optimally. Significant at p0.05. Selected animal groups do dislocation of the neck, pancreatic tissue taken and then preserved using formalin. Histopathologic examination and pancreatic tissue was observed qualitatively. The results showed dose administration of 200 mg / 20g BW can lower blood glucose levels compared with the positive and negative control group and showed clear improvement tissue in the group with a dose of 200 mg / 20 g BW.
机译:关于从大豆发酵豆获得的大豆面粉中含有豆面粉中含有豆粉的效果的研究到胰腺β细胞的改善。在治疗前,甲氧烷化合物诱导的小鼠胰腺。样品选择后,通过提供3种变异剂量的柔性面粉进行治疗的小鼠是40mg; 55; 75; 105; 145和200 mg / 20g bw。将小鼠分为8组,第1组是一组阴性对照而不提供任何内容,第2组是阳性对照,糖尿病小鼠组不提供处理,给出3,4,5,6,7和8组,给出3,4,5,6,7和8组群临时面粉6剂量变异。由于本研究的参数是在第7天测量小鼠的血糖水平;第14和第21届。该方法使用“魅力博士”使用酶法。给予Tempeh粉的一组老鼠,观察到的剂量,可以在最佳地提供血糖水平降低。 P <0.05的显着显着。选定的动物群体脱位颈部,胰腺组织捕获,然后使用福尔马林保留。定性观察组织病理学检查和胰腺组织。结果表明,与阳性和阴性对照组相比,对血糖水平降低血糖水平的剂量给药,并在组中显示出澄清的改善组织,剂量为200mg / 20g bw。

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