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首页> 外文期刊>Journal of Applied Animal Research >Associations between MUC1 gene polymorphism and resistance to mastitis, milk production and fertility traits in Murrah water buffaloes sup*/sup * F.T. Rosa. Dairy, reproductive and healthy traits are important economical polygenic traits in dairy herds. MUC1 gene can be an important molecular marker that influences these traits and can cause beneficial impacts in the costs of dairy industry. View all notes
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Associations between MUC1 gene polymorphism and resistance to mastitis, milk production and fertility traits in Murrah water buffaloes sup*/sup * F.T. Rosa. Dairy, reproductive and healthy traits are important economical polygenic traits in dairy herds. MUC1 gene can be an important molecular marker that influences these traits and can cause beneficial impacts in the costs of dairy industry. View all notes

机译：MUC1基因多态性与摩尔水牛水牛牛奶生殖和肥育性质的抗性的关联 * * f.t.罗莎。乳品，生殖和健康的特质是乳制品牛群中的重要经济性多种状体性状。 Muc1基因可以是影响这些特征的重要分子标记，并可能导致乳制品业的收益产生有益的影响。查看所有笔记

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摘要

MUC1 is a glycoprotein mucin expressed in apical cells of luminal tissues, such as mammary gland luminal cells, which the main function is protect the cell surface from the environment microorganisms. The aim of this study were to identify the polymorphism of MUC1 gene in Murrah breed and to analyze the association between molecular marker and somatic cell counting, milk yield, fat yield, fat percentage, protein yield, protein percentage, age at first calving and calving interval. A total of 179 primiparous Murrah buffaloes were genotyped by PCR technique. Milk-recording were performed periodically to determine fat and protein content and somatic cell count. Three alleles of different lengths were amplified and named allele 1, 2 and 3, respectively. The allele 2 was more frequent followed by allele 3. The MUC1 gene was highly associated with traits related to mastitis resistance and milk percentage. Also was demonstrated a mild association between MUC1 gene and milk protein synthesis and a moderate effect on reproductive trait. The MUC1 gene is polymorphic in water buffaloes of Murrah breed and might be a potential marker to marker-assisted selection for intramammary infection and some milk production traits.
机译：MUC1是在腔组织的顶端细胞中表达的糖蛋白粘蛋白，例如乳腺腔细胞，主要功能免受环境微生物保护细胞表面。本研究的目的是鉴定Murrah品种中Muc1基因的多态性，并分析分子标记和体细胞计数之间的关联，牛奶产量，脂肪产量，脂肪百分比，蛋白质产量，蛋白质百分比，年龄在第一次犊牛和犊牛间隔。通过PCR技术共有179个初步穆雷拉水牛进行基因分型。定期进行牛奶记录以确定脂肪和蛋白质含量和体细胞计数。分别扩增三个不同长度的等位基因，并分别命名等位基因1,2和3。等位基因2更频繁，其次是等位基因3. MUC1基因与与乳腺炎抗性和牛奶百分比相关的性状高度相关。还在Muc1基因和牛奶蛋白合成与对生殖性状的中度效应之间进行了态度。 MUC1基因是Murrah品种的水牛中的多态性，可能是对脑内感染和一些牛奶生产性状的标记辅助选择的潜在标志物。

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