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首页> 外文期刊>Journal of Cancer Research and Therapeutics >Clinical outcome of 30 patients with bone marrow metastases
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Clinical outcome of 30 patients with bone marrow metastases

机译：30例骨髓转移患者的临床结果

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Objective: Cancer patients with bone marrow metastases are rare and dismal. The study was to identify the clinical features and prognostic factors in cancer patients with bone marrow metastases. Patients and Methods: A total of 30 patients with bone marrow metastases were reviewed between September 2007 and September 2013. Bone marrow metastases were identified by bone marrow aspiration. Results: The median age was 56.5 years (range, 8–85 years). The two most common primary tumor sites were the stomach (7, 23.3%), breast (5, 16.7%). Bone metastases (27, 90.0%) were the most common concurrent metastases. The most common cause for bone marrow aspiration was anemia and thrombocytopenia (10, 33.3%). The median survival time was 3 months (range, 0.5–82 months). Patients with good performance status (n = 19) had a longer median survival time than patients with poor performance status (n = 11) (8 months vs. 1 months, P = 0.041). Patients with primary unknown origin (n = 5) had a significantly shorter overall survival time than patients with known origin (n = 25) (1 month vs. 6 months = 0.010). The median survival time was 9 months in the systemic therapy group (n = 21) and 1 month in the best supportive care group (n = 9) (P = 0.000). Conclusion: To make primary origin clear and start systemic antitumor therapy is beneficial for patients with bone marrow metastases.
机译：目的：患有骨髓转移率的癌症患者是罕见和令人沮丧的。该研究是鉴定癌症患者骨髓转移患者的临床特征和预后因素。患者和方法：2007年9月至2013年9月期间，共审查了30例骨髓转移患者。通过骨髓抽吸鉴定骨髓转移。结果：中位年龄为56.5岁（范围，8-85岁）。两种最常见的主要肿瘤部位是胃（7,23.3％），乳房（5,16.7％）。骨转移（27,90.0％）是最常见的并发转移。骨髓抽吸最常见的原因是贫血和血小板减少症（10,33.3％）。中位生存时间为3个月（范围，0.5-82个月）。性能良好状态（n = 19）的患者具有比性能状况不佳的患者更长的生存时间（n = 11）（8个月与1个月，p = 0.041）。患有初级未知来源的患者（n = 5）的总生存时间明显较短，而不是已知起源的患者（n = 25）（1个月对6个月= 0.010）。中位生存时间为9个月在全身治疗组（n = 21）和最佳支持护理组（n = 9）中的1个月（p = 0.000）。结论：使原发性起源清晰，启动全身抗肿瘤治疗对骨髓转移患者有益。

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