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The Role of Interventional Radiology for the Treatment of Hepatic Metastases from Neuroendocrine Tumor: An Updated Review

机译:介入放射学对神经内分泌肿瘤治疗肝转移的作用:更新综述

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Interventional radiology plays an important role in the management of patients with neuroendocrine tumor liver metastasis (NELM). Transarterial embolization (TAE), transarterial chemoembolization (TACE), and selective internal radiation therapy (SIRT) are intra-arterial therapies available for these patients in order to improve symptoms and overall survival. These treatment options are proposed in patients with NELM not responding to systemic therapies and without extrahepatic progression. Currently, available data suggest that TAE should be preferred to TACE in patients with NELM from extrapancreatic origin because of similar efficacy and better patient tolerance. TACE is more effective in patients with pancreatic NELM and SIRT has shown promising results along with good tolerance. However, large randomized controlled trials are still lacking in this setting. Available literature mainly consists in small sample size and retrospective studies with important technical heterogeneity. The purpose of this review is to provide an updated overview of the currently reported endovascular interventional radiology procedures that are used for the treatment of NELM.
机译:介入放射学在神经内分泌肿瘤肝转移患者(NELM)的管理中起着重要作用。常规栓塞(TAE),rantarterial Chemoembolization(TACE)和选择性内部放射治疗(SIRT)是可用于这些患者的动脉内疗法,以改善症状和整体存活。在NELM患者中提出了这些治疗方案,没有响应全身疗法,没有侵袭性进展。目前,可用的数据表明,由于类似的功效和更好的患者耐受性,TAE应该优选NELM患者的TACE。 TACE在胰腺NELM患者中更有效,SIRT都表明了有希望的结果以及良好的耐受性。然而,这个环境仍然缺乏大型随机对照试验。可用文献主要包括小型和回顾性研究,具有重要的技术异质性。本综述的目的是提供当前报告的血管内介入放射学程序的更新概述,用于治疗NELM。

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