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首页> 外文期刊>Journal of Clinical Medicine >Motor Control Stabilisation Exercise for Patients with Non-Specific Low Back Pain: A Prospective Meta-Analysis with Multilevel Meta-Regressions on Intervention Effects
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Motor Control Stabilisation Exercise for Patients with Non-Specific Low Back Pain: A Prospective Meta-Analysis with Multilevel Meta-Regressions on Intervention Effects

机译：非特异性低腰痛患者的电机控制稳定运动：介入效果对多级元回归的预期荟萃分析

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Low-to-moderate quality meta-analytic evidence shows that motor control stabilisation exercise (MCE) is an effective treatment of non-specific low back pain. A possible approach to overcome the weaknesses of traditional meta-analyses would be that of a prospective meta-analyses. The aim of the present analysis was to generate high-quality evidence to support the view that motor control stabilisation exercises (MCE) lead to a reduction in pain intensity and disability in non-specific low back pain patients when compared to a control group. In this prospective meta-analysis and sensitivity multilevel meta-regression within the MiSpEx-Network, 18 randomized controlled study arms were included. Participants with non-specific low back pain were allocated to an intervention (individualized MCE, 12 weeks) or a control group (no additive exercise intervention). From each study site/arm, outcomes at baseline, 3 weeks, 12 weeks, and 6 months were pooled. The outcomes were current pain (NRS or VAS, 11 points scale), characteristic pain intensity, and subjective disability. A random effects meta-analysis model for continuous outcomes to display standardized mean differences between intervention and control was performed, followed by sensitivity multilevel meta-regressions. Overall, 2391 patients were randomized; 1976 (3 weeks, short-term), 1740 (12 weeks, intermediate), and 1560 (6 months, sustainability) participants were included in the meta-analyses. In the short-term, intermediate and sustainability, moderate-to-high quality evidence indicated that MCE has a larger effect on current pain (SMD = ?0.15, ?0.15, ?0.19), pain intensity (SMD = ?0.19, ?0.26, ?0.26) and disability (SMD = ?0.15, ?0.27, ?0.25) compared with no exercise intervention. Low-quality evidence suggested that those patients with comparably intermediate current pain and older patients may profit the most from MCE. Motor control stabilisation exercise is an effective treatment for non-specific low back pain. Sub-clinical intermediate pain and middle-aged patients may profit the most from this intervention.
机译：低于适度的质量元分析证据表明，电机控制稳定运动（MCE）是对非特异性低背疼痛的有效处理。克服传统荟萃分析弱点的可能方法是预期荟萃分析的弱点。本分析的目的是产生高质量的证据，以支持电机控制稳定锻炼（MCE）导致与对照组相比，非特异性低腰疼痛患者的疼痛强度和残疾降低。在MISPEX网络中的这种预期元分析和敏感性多级元回归中，包括18个随机对照研究武器。具有非特异性低背疼痛的参与者被分配给干预（个体化MCE，12周）或对照组（没有添加剂运动干预）。从每个研究现场/ ARM，基线的结果，3周，12周和6个月合并。结果是目前疼痛（NRS或VAS，11分，表达），特征疼痛强度和主观残疾。对连续结果进行随机效应，以显示在涉及干预和控制之间显示标准化平均差异的情况下进行，随后是敏感性多级元回归。总体而言，2391名患者随机化; 1976年（3周，短期），1740（12周，中级）和1560（6个月，可持续性）参与者被列入Meta-Analys中。在短期，中间和可持续性方面，中等至高质量的证据表明，MCE对电流疼痛的影响较大（SMD = 0.15，？0.15，？0.19），疼痛强度（SMD =？0.19，？0.26与无运动干预相比，α06）和残疾（SMD =Δ0.15，？0.27，？0.25）。低质量的证据表明，那些具有相当中间疼痛和老年患者的患者可能来自MCE的最大损益。电机控制稳定运动是对非特异性低腰痛的有效处理。亚临床中间疼痛和中年患者可能从这种干预中获利。

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