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Common Musculoskeletal Disorders in the Elderly: The Star Triad

机译:常见的肌肉骨骼疾病在老年人:星星三合会

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Musculoskeletal disorders are debilitating conditions that significantly impair the state of health, especially in elderly subjects. A pathological triad of inter-related disorders that are highly prevalent in the elderly consists of the following main “components”: sarcopenia, tendinopathies, and arthritis. The aim of this review is to critically appraise the literature relative to the different disorders of this triad, in order to highlight the pathophysiological common denominator and propose strategies for personalized clinical management of patients presenting with this combination of musculoskeletal disorders. Their pathophysiological common denominator is represented by progressive loss of (focal or generalized) neuromuscular performance with a risk of adverse outcomes such as pain, mobility disorders, increased risk of falls and fractures, and impaired ability or disability to perform activities of daily living. The precise management of these disorders requires not only the use of available tools and recently proposed operational definitions, but also the development of new tools and approaches for prediction, diagnosis, monitoring, and prognosis of the three disorders and their combination.
机译:肌肉骨骼障碍是衰弱的条件,即大大损害健康状况,特别是在老年人的患者中。老年人在老年人中普遍普遍的相关疾病的病理学三合会包括以下主要的“组件”:Sarcopenia,肌腱病和关节炎。本综述的目的是批判性地评估与该三合会的不同疾病的文献,以突出病理生理学共同的分母,并提出患有这种肌肉骨骼疾病组合的患者的个性化临床管理的策略。它们的病理生理学常见的分母由渐进式丧失(焦点或广义)神经肌肉表现具有不良成果的风险,例如疼痛,迁移障碍,跌倒和骨折的风险增加,以及执行日常生活活动的受损能力或残疾的风险。这些障碍的确切管理不仅需要使用可用工具和最近提出的操作定义,而且还需要开发新工具和三种疾病的预测,诊断,监测和预后的方法及其组合的方法。

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