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首页> 外文期刊>Journal of Clinical Medicine Research >The Elevation of Cardio-Ankle Vascular Index in a Patient With Malignant Lymphoma Treated With a Combination Therapy of Rituximab and Cyclophosphamide, Doxorubicin, Vincristine, and Prednisolone
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The Elevation of Cardio-Ankle Vascular Index in a Patient With Malignant Lymphoma Treated With a Combination Therapy of Rituximab and Cyclophosphamide, Doxorubicin, Vincristine, and Prednisolone

机译：用Rituximab和环磷酰胺的组合治疗，多柔比星，长春酮和泼尼松龙治疗恶性淋巴瘤患者心脏 - 踝血管指数的升高

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An increased risk of arteriosclerosis has been noted in cancer survivors. Currently, there are only a few reports available that consider the risk of arteriosclerosis in patients treated with chemotherapy. Patients with an advanced stage B-cell malignant lymphoma are typically treated with a combination therapy of rituximab and cyclophosphamide, doxorubicin, vincristine, and prednisolone (R-CHOP). Complications such as diabetes mellitus (DM), hyperlipidemia (HL), and osteoporosis due to prednisolone and cardiotoxicity due to anthracyclines are well known. However, there are no studies that have investigated the link between R-CHOP therapy and arteriosclerosis. We discussed a patient with follicular lymphoma who was evaluated using cardio-ankle vascular index (CAVI) as an arterial stiffness parameter during R-CHOP therapy in this report. She achived complete remission after the eighth course therapy without complications such as hypertension (HT), HL, DM, and infection. This patient showed elevated CAVI with new plaque formation in the carotid arteries after the end of chemotherapy. These data indicate that R-CHOP therapy may progress the arteriosclerosis.J Clin Med Res. 2017;9(8):729-732doi: https://doi.org/10.14740/jocmr3071w
机译：在癌症幸存者中发现了动脉硬化的风险增加。目前，只有几份报告可用，以考虑化疗治疗患者动脉硬化的风险。高级B细胞恶性淋巴瘤的患者通常用Rituximab和环磷酰胺，多柔比蛋白，长春螯合物和泼尼松（R-Chec）的组合治疗治疗。众所周知，糖尿病（DM），高脂血症（HL），高脂血症（HL）和骨质疏松症等并发症是众所周知的。然而，没有研究R-Chec疗法和动脉硬化之间的联系。我们讨论了患有滤泡淋巴瘤的患者，在本报告中使用心脏 - 踝血管指数（CAVI）作为动脉僵硬参数进行评估。她在第八课程治疗后的完全缓解，没有高血压（HT），HL，DM和感染等并发症。该患者在化疗结束后颈动脉中的新斑块形成升高。这些数据表明R-Chec疗法可能进展ArteriosClerosis.j Clin Med Res。 2017; 9（8）：729-732DOI：https://doi.org/10.14740/jocmr3071w

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