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Epidemiology of Infective Endocarditis in Rural Upstate New York, 2011 - 2016

机译:纽约农村北北部感染性心内膜炎的流行病学,2011年 - 2016年

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Background: The epidemiology of infective endocarditis (IE) depends on a number of host factors whose prevalence can vary globally. The usual patient population affected by IE is sicker and older, often with many comorbid conditions. The risk is growing in younger populations due to the emerging epidemic of intravenous (IV) drug use. We have performed a temporal trend analysis of various factors of IE in the rural counties covering a major part of central Upstate New York.Methods: We performed a retrospective analysis of electronic medical records of patients who were admitted in a tertiary care hospital in rural Upstate New York and diagnosed with IE from January 1, 2011 to December 31, 2016. Forty-five patients were identified with definite IE and nine with possible IE.Results: Total incidence of IE was 3.5 cases per 100,000 person years in the total population and 4.4 if we consider total population ≥ 18 years in the denominator. A significant (P = 0.022) increase in incidence of IE from 2011 to 2016 was seen by univariate analysis. Incidence was higher in males (P = 0.029) and for those aged 65 or older (P = 0.0003). IV drug use among cases is noted to be more prevalent in 2015 and 2016 compared to previous years.Conclusion: In this study of patients in a rural region of New York, an increase in the incidence of IE was seen over the study period with changes in patient characteristics and etiology over this time. We speculate that an increase in IV drug use could be a leading factor in the recent and future increased incidence of IE in the area.J Clin Med Res. 2017;9(9):754-758doi: https://doi.org/10.14740/jocmr3131w
机译:背景:感染性心内膜炎(IE)的流行病学取决于许多寄生因子,其流行可能会在全球范围内各不相同。通常受IE的患者人口是恶病人和更老的,通常是许多合并症的条件。由于静脉注射(IV)药物使用的新兴流行病,风险在较年轻的群体中增长。我们已经对IE中的各种因素进行了时间趋势分析,涵盖了纽约中央北斯特州中部的主要部分的各种因素。方法:我们对在农村北北部的第三级护理医院承认的患者的电子医疗记录进行了回顾性分析纽约和2011年1月1日诊断为2016年1月1日至2016年12月31日。四十五名患者用明确的IE和九个患者确定了IE.Results:IE的总发生率为每10万人每年3.5例,总人口4.4如果我们认为分母中总人口≥18岁。单位分析观察到从2011年到2016年的IE发病率的显着(p = 0.022)。雄性的发病率较高(P = 0.029),并为65岁或以上的(P = 0.0003)。 IV案例中的药物使用在2015年和2016年的情况下,与前几年相比更为普遍。结论:在这项纽约乡村患者的研究中,在研究期内,在研究期内看到了IE的发生率增加在这次患者的特征和病因中。我们推测IV药物使用的增加可能是最近和未来的IE中的发病率的主要因素。 2017; 9(9):754-758DOI:https://doi.org/10.14740/jocmr3131w

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