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首页> 外文期刊>Journal of Clinical Medicine Research >Efficacy of Intravenous Administration of Landiolol in Patients With Acute Heart Failure and Supraventricular Tachyarrhythmia
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Efficacy of Intravenous Administration of Landiolol in Patients With Acute Heart Failure and Supraventricular Tachyarrhythmia

机译：静脉内施用Landiolol在急性心力衰竭患者中的​​疗效和Supraventriculardrallythmia

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Background: Patients with acute heart failure (HF) complicated by supraventricular tachyarrhythmia (SVT) often receive continuous intravenous infusion of landiolol or diltiazem for rate control. It is unclear whether the interval from initiation of infusion to commencement of oral beta-blocker (BB) therapy differs for these two drugs.Methods: From January 2013 to July 2015, 94 consecutive patients were hospitalized for acute HF complicated by SVT. After 35 patients were excluded, the remaining 59 were divided into groups treated with diltiazem or landiolol. We investigated the blood pressure, heart rate, New York Heart Association classification, brain natriuretic peptide, chest X-ray film, echocardiographic findings (ejection fraction (EF)), time until commencement of oral BB therapy, and hospital stay.Results: There were no significant between-group differences of heart rate, blood pressure, or the severity of HF. The time until commencing oral BB therapy was significantly shorter in the landiolol group compared with the diltiazem group (median: 2 vs. 4 days, P = 0.002), but there was no significant difference in hospital stay. This interval was significantly shorter in patients with a reduced EF in the landiolol group (median: 2 days) compared with those with a reduced EF in the diltiazem group (median: 5 days, P = 0.008), and patients with a preserved EF in the landiolol group tended to have a shorter interval (median: 2 days) than those with a preserved EF in the diltiazem group (median: 4 days, P = 0.092).Conclusions: Switching to oral BBs was accomplished earlier with landiolol than with diltiazem.J Clin Med Res. 2017;9(5):426-432doi: https://doi.org/10.14740/jocmr2954w
机译：背景：急性心力衰竭（HF）的患者通过Supraventriculary Tachyarrhalythmia（SVT）复杂，通常接受Landiolol或Diltizem的连续静脉内输注速率控制。目前尚不清楚将输注引发的间隔是否与口腔β-阻滞剂（BB）疗法开始的间隔不同于这两种药物。方法：从2013年1月到2015年7月，94名连续患者因SVT复杂的急性HF住院。排除35例患者后，将剩余的59分为用Diltiazem或Landiolol治疗的组。我们调查了血压，心率，纽约心脏关联分类，脑利率肽，胸部X射线膜，超声心动图（EF分数（EF）），直至开始口腔BB治疗，以及住院留下来。结果：那里对心率，血压或HF严重程度的组差异无显着。与Diltiazem组相比，Landiolol组中，在Landiolol Group（中位数：2与4天，P = 0.002）相比，直到开始口服BB疗法的时间明显较短，但住院住院差异没有显着差异。与Diltiazem组（中位数：5天，P = 0.008）中的EF减少（中位数：2天），这种间隔减少了患者的患者患者显着较短Landiolol组往往比Diltiazem组的保存EF的间隔（中位数：2天）往返于那些.J Clin Med Res。 2017; 9（5）：426-432DOI：https://doi.org/10.14740/jocmr2954w

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