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首页> 外文期刊>Journal of Clinical Medicine Research >Risk of Stroke in Patients With Patent Foramen Ovale Who Had Pulmonary Embolism
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Risk of Stroke in Patients With Patent Foramen Ovale Who Had Pulmonary Embolism

机译：患有肺栓塞的专利诱饵卵巢患者中风的风险

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Background:The presence of patent foramen ovale (PFO) alone does not increase the risk of ischemic stroke. Several prospective studies with a small number of patients have shown that the risk of ischemic stroke is higher in patients with PFO and pulmonary embolism (PE). We studied the association of ischemic stroke in the patients who had PFO with PE (PFOwiPE) and compared with the patients who had PFO without PE (PFOwoPE).Methods:Electronic medical records of 154 adult patients in our internal medicine office were reviewed. Thirty-four patients had PFOwiPE and 120 had PFOwoPE. Independent t-test and Mann-Whitney U-test were used to compare the continuous variables between the two groups, while Chi-square tests were applied to compare the categorical variables between the two groups. Logistic regression was used for multivariate analysis. The dependent variable was stroke and the independent variable of interest was PFO with, or without PE.Results:Mean age of patients with PFOwiPE was 54.8 years and patients with PFOwoPE was 57.8 years (P = 0.331). Mean body mass index (BMI) of the patients with PFOwiPE was significantly greater than the patients with PFOwoPE (32.5 ± 8.84 kg/m2 vs. 28.4 ± 6.99 kg/m2; P 0.05). Mean left ventricular ejection fraction (LVEF) and red blood cell (RBC) count of patients with PFOwiPE was significantly lower than patients with PFOwoPE (LVEF 54.9 ± 13.01% vs. 59.6 ± 6.85%, P 0.05; RBC 4.1 ± 1.203 × 106/μL vs. 4.5 ± 0.596 × 106/μL, P 0.05). There was significantly higher association of congestive heart failure (CHF) in patients with PFOwiPE compared to patients with PFOwoPE (20.6% vs. 7.5%; P 0.05). Association of ischemic stroke was 35.3% in patients with PFOwiPE and 39.2% in patients with PFOwoPE. The difference was not statistically significant (P = 0.682).Conclusions:Association of ischemic stroke was similar in patients with PFOwiPE and patients with PFOwoPE. Association of significantly higher BMI, lower LVEF, lower RBC count, and higher frequency of CHF were associated with patients with PFOwiPE compared to the patients with PFOwoPE.Copyright 2020, Roy et al.
机译：背景：单独的专利ovale（PFO）的存在不会增加缺血性卒中的风险。具有少数患者的几项前瞻性研究表明，PFO和肺栓塞患者（PE）患者缺血性卒中风险较高。我们研究了患有PE（PFOWIPE）的PFO患者缺血性卒中协会，并与没有PE的PFO（PFOWOPE）的患者相比。方法：审查了154名成人患者的电子医疗记录。三十四名患者有PFOWIPE，120患者有PFOWOPE。独立的T检验和Mann-Whitney U-Test用于比较两组之间的连续变量，而Chi-Square测试应用于比较两组之间的分类变量。 Logistic回归用于多变量分析。受抚养变量是行程，兴趣的独立变量是PFO，或者没有PE.Results：PFOWIPE患者的平均年龄为54.8岁，PFOWOPE患者为57.8岁（P = 0.331）。 PFOWIPE患者的平均体重指数（BMI）明显大于PFOWOPE患者（32.5±8.84kg / m 2 vs.28.4±6.99 kg / m 2; p <0.05）。 PFOWIPE患者的平均左心室喷射分数（LVEF）和红细胞（RBC）计数明显低于PFOWOPE的患者（LVEF 54.9±13.01％Vs.59.6±6.85％，P <0.05; RBC 4.1±1.203×106 /μlvs.4.5±0.596×106 /μl，p <0.05）。与PFOWOPE患者相比，PFOWIPE患者的充血性心力衰竭（CHF）结合显着更高（20.6％vs.7.5％; P <0.05）。 PFOWIPE患者缺血性中风的关联患者为35.3％，PFOPOPE患者39.2％。差异在统计学上没有统计学意义（p = 0.682）。结论：缺血性脑卒中的关联在pFOWIPE和PFOWOPE患者的患者中相似。与PFOWope患者相比，与PFOWOPE患者相比，与PFOWOPE.COPYRIGHT 2020，ROY等人相比，CHF患者的患者有显着较高的BMI，降低的LVEF，较低的RBC计数和较高频率与PFWOWIPE的患者有关。

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