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首页> 外文期刊>Journal of Clinical Sciences >An interesting story of intravascular hemolysis but normal haptoglobin and bilirubin levels
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An interesting story of intravascular hemolysis but normal haptoglobin and bilirubin levels

机译：血管内溶血的一个有趣的故事，但正常的哈帕替洛博林和胆红素水平

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摘要

Multiple bee stings are associated with intravascular hemolysis (IVH), rhabdomyolysis, hypotension, renal tubule injury, and all causing acute kidney injury. Evidence in support of hemolysis includes anemia, hyperbilirubinemia, hemoglobinemia, hemoglobinuria, low haptoglobin (Hp) levels, elevated lactate dehydrogenase, and Coomb's test (if antibody mediated). However, under certain circumstances, hemoglobinemia and hemoglobinuria may be the only evidence of IVH depending on the etiological factors in association with the environment inside the body. Bee venom is known to have deleterious actions on different tissue types (neurotoxin, muscle paralytic, hematotoxic, epithelial damage, etc.). Altogether, they determine the outcome and presentation. Apart from this, there are several conditions that determine the binding of oxygen and Hp to hemoglobin (Hb). Arterial blood gases (ABGs) play a very important role in this. Hence, it is important for the pathologists to have an understanding of ABG as well to know how even simple tests (Hb, bilirubin, and Hp) can get affected by them. We describe one such occurrence in a patient with multiple hornet bee stings and formulate the likely causes and pathogenesis.
机译：多只蜂蜇料与血管内溶血（IVH），横纹肌溶解，低血压，肾小管损伤相关，并且所有导致急性肾损伤。支持溶血的证据包括贫血，高胆血清血症，血红蛋白血症，血红蛋白，低哈达氟胺（HP）水平，升高的乳酸脱氢酶和COOMB的测试（如果抗体介导）。然而，在某些情况下，血红蛋白血症和血红蛋白可能是IVH的唯一证据，具体取决于与身体内部环境相关的病因因素。已知蜜蜂毒液对不同的组织类型（神经毒素，肌肉麻痹，血管毒性，上皮损伤等）具有有害的作用。总的来说，他们决定了结果和演示。除此之外，还有几种条件，可确定氧气和HP与血红蛋白（HB）的结合。动脉血液（ABG）在这方面发挥着非常重要的作用。因此，本病理学家对ABG的理解是很重要的，并知道甚至可以如何影响它们的简单测试（HB，Biilirubin和HP）。我们描述了具有多个大黄蜂蜂巢的患者中的一种这种发生，并配制可能的原因和发病机制。

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