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Correlation of neutrophil–lymphocyte ratio with disease activity in rheumatoid arthritis

机译:类风湿性关节炎疾病活性的中性粒细胞淋巴细胞比的相关性

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Background: Neutrophil–lymphocyte ratio (NLR) is reported to be increased in various inflammatory conditions, but its significance in RA remains unclear. The aim of this study was to evaluate whether NLR can be used as a simple tool for disease activity assessment in rheumatoid arthritis (RA). Aim: The aim was to assess the NLR in RA patients and compare between active cases and those in remission. Materials and Methods: The study enrolled 150 diagnosed RA patients. Disease activity was determined with the Disease Activity Score (DAS-28), and the correlation of NLR with disease activity was analyzed. Results: NLR, C-reactive protein (CRP), and erythrocyte sedimentation rate (ESR) were found to be significantly high in RA patients. Further, NLR correlated positively with CRP, ESR, and worsening DAS score. Conclusion: Our study concludes that NLR can become a readily available and cost-effective tool for disease assessment in RA in future.
机译:背景:据报道,中性粒细胞淋巴细胞比(NLR)在各种炎症条件下增加,但其在RA中的重要性仍不清楚。本研究的目的是评估NLR是否可以用作类风湿性关节炎(RA)中的疾病活动评估的简单工具。目的:目的是评估RA患者的NLR,并在活动案例和缓解方面进行比较。材料和方法:研究注册了150例诊断的RA患者。用疾病活动评分(DAS-28)测定疾病活性,分析了NLR与疾病活动的相关性。结果:NLR,C-反应蛋白(CRP)和红细胞沉积率(ESR)在RA患者中被发现显着高。此外,NLR与CRP,ESR和恶化DAS得分正相关。结论:我们的研究得出结论,NLR可以成为未来RA疾病评估的易用和经济效益的工具。

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