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首页> 外文期刊>Journal of Clinical Sciences >Urinary tract infections and antimicrobial susceptibility pattern among female students in a tertiary institution in southwest Nigeria - A cross sectional study
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Urinary tract infections and antimicrobial susceptibility pattern among female students in a tertiary institution in southwest Nigeria - A cross sectional study

机译：西南尼日利亚西南三级机构女学生患者尿路感染与抗微生物敏感性模式 - 横截面研究

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Background: Urinary tract infections (UTIs) is a common medical problem that affects all age groups but with significant morbidity in females because of the nature of their anatomy and physiology. This study was aimed to identify the common causative organisms of UTI and their antimicrobial susceptibility pattern among female students in Babcock University. Methods: A cross-sectional study, in which 200 female participants with symptoms of UTI were recruited. Mid-stream urine was collected from them and processed using the standard microbiological procedures. Antimicrobial susceptibility testing was performed on isolates from the samples with significant bacteriuria. Sociodemographic and risk factors were obtained using standard questionnaires, and statistical analysis was performed using SPSS version 23.0. Results: UTIs were confirmed in 14.5% (29/200) participants. Of the pathogens isolated, Escherichia coli was predominant 30.6% (11/36). Most of the pathogens isolated were susceptible to ofloxacin and gentamicin, while ceftriaxone had the least susceptibility (18.2%). The majority of the participants, 165 (82.5%) though symptomatic, did not have bacteriuria. The participants aged 15–20 years were mostly infected [24 (13.4%)]. No significant association was found between the sociodemographic factors and UTI. Conclusion: The prevalence of UTI from this study was 14.5%. E. coli was the predominant bacteria pathogen isolated, and ofloxacin and gentamycin were the most active antibiotics on susceptibility pattern. The majority of the patients though symptomatic, had no pathogens isolated from their urine. Therefore, caution should be applied on the use of antibiotics when managing UTI based on symptoms alone, to prevent antibiotic resistance.
机译：背景：尿路感染（UTI）是一种常见的医学问题，影响所有年龄组，但由于其解剖和生理学的性质，女性的发病率具有显着的发病率。本研究旨在鉴定Babcock大学女学生uti及其抗微生物易感模式的常见致病生物。方法：围绕横断面研究，其中招募了200名患有UTI症状的女性参与者。从它们中收集中流尿液并使用标准微生物方法处理。对具有显着细菌的样品的分离物进行抗微生物敏感性测试。使用标准问卷获得社会阶段和风险因素，并使用SPSS版本23.0进行统计分析。结果：Utis于14.5％（29/200）参与者中确认。孤立的病原体，大肠杆菌主要是30.6％（11/36）。分离的大多数病原体易受氧氟沙星和庆大霉素的影响，而头孢曲松的敏感性最低（18.2％）。大多数参与者，165（82.5％）虽然症状，没有细菌。 15-20岁的参与者主要感染[24（13.4％）]。在社会渗塑因素和UTI之间没有发现任何重大关联。结论：本研究中UTI的患病率为14.5％。大肠杆菌是分离的主要细菌病原体，氧氟沙星和庆大霉素是易感模式中最活跃的抗生素。大多数患者虽然症状，没有尿液中分离出病原菌。因此，应在基于单独症状管理UTI时谨慎使用抗生素，以防止抗生素抗性。

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