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首页> 外文期刊>Journal of Environmental Science and Technology >Thyroid Dysfunction among School-Aged Children due to Chronically Excessive Iodine Groundwater, Central Java, Indonesia
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Thyroid Dysfunction among School-Aged Children due to Chronically Excessive Iodine Groundwater, Central Java, Indonesia

机译：学龄前儿童甲状腺功能障碍，由于慢性过量的碘地下水，中爪哇省，印度尼西亚

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Background and Objective: Iodine excess is a risk factor in thyroid dysfunction. The purpose of the study was to identify the prolonged effect of iodine excess on thyroid dysfunction in areas with high iodine on natural resources in Indonesia. Materials and Methods: A cross-sectional study was conducted in two districts. This study included 500 School-Aged Children (SAC) 06-12 years of age for 25 clusters in each district, were included in this study. Logistic regression was performed to estimate the risk of thyroid dysfunction. Results: Demak and Grobogan were classified as iodine excess area with Median Urine Iodine Concentration (MUIC) is 446, 453 μg Lsup?/supsup1/sup, iodine water at 112.3, 414.5 ppb. Profile thyroid dysfunction was described as subclinical hypothyroidism, 31.5, 36.3%, secondary hypothyroidism, 25.5, 6.9%, respectively. While autoimmune thyroiditis was not shown, overt and subclinical hyperthyroidism was found in Grobogan only 0.4;1.4%. Excess iodine raises the risk of subclinical hypothyroidism, Adjusted Odd Ratio (AOR): 1.97 (CI:1.1-3.4) and secondary hypothyroidism, AOR: 2.44 (CI:1.5-3.9). Conclusion: Subclinical hypothyroidism is the most prevalent thyroid disease in iodine excess area due to elevated iodine in groundwater.
机译：背景和目的：碘过量是甲状腺功能障碍的危险因素。该研究的目的是鉴定碘过量对甲状腺功能障碍的延长效应，在印度尼西亚的高碘基础上具有高碘基础。材料和方法：在两个地区进行了横截面研究。本研究包括每区别25个群集的500名学龄儿童（SAC）06-12岁，纳入这项研究。进行逻辑回归以估计甲状腺功能障碍的风险。结果：Demak和Grobogan被分类为碘过量区域，中值碘浓度（MUIC）是446,453μgLαs，碘水，112.3，414.5 ppb。型材甲状腺功能障碍被描述为亚临床甲状腺功能亢进，31.5,36.3％，二次甲状腺功能亢进，分别为25.5,6.9％。虽然未显示自身免疫性甲状腺炎，但在Grobogan中发现了公开和亚临床甲状腺功能亢进症仅为0.4; 1.4％。过量的碘会引发亚临床甲状腺功能减退症的风险，调整奇数（AOR）：1.97（CI：1.1-3.4）和次生甲状腺功能减退症，AOR：2.44（CI：1.5-3.9）。结论：由于地下水中碘升高，亚临床甲状腺功能减退症是碘过量区域中最普遍的甲状腺疾病。

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