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Does binge-eating matter for glycemic control in type 2 diabetes patients?

机译:2型糖尿病患者血糖对照的血液治疗吗?

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Eating behavior is an important aspect related to type 2 diabetes mellitus (T2DM) treatment and may have an impact on glycemic control. Previous reports showed elevated prevalence of eating disordered behaviors, especially binge eating disorder in clinical samples of type 2 diabetes patients. However, results regarding the impact of an eating disorder on the glycemic and clinical control of T2DM is inconsistent. The purpose of this study was to assess the impact of a comorbid eating disorder on glycemic control (GC) in a group of patients with T2DM. Eating behaviors of 70 consecutive patients with T2DM were assessed using a Structured Clinical Interview for DSM-IV and the Binge Eating Scale. The GC was examined with fasting blood glucose (FBG) and glycated hemoglobin (A1c) levels. In addition, secondary clinical variables were assessed, including body mass index (BMI) and lipids. Chi-square and Student's T tests were used to compare clinical and psychopathological characteristics of patients with and without an ED. In order to evaluate the relationship between GC and eating disorder (ED) a linear regression analysis was performed, controlling for BMI. A significance level of 5% was adopted. Seventy-seven percent of the sample (n?=?54) were female and 50% were obese. Fourteen patients exhibited an ED, mostly binge eating disorder (BED). In a regression analysis, both FBG (beta coefficient?=?47.4 (22.3); p?=?0.037) and A1c (beta coefficient?=?1.12 (0.57); p?=?0.05) were predicted by the presence of an ED. However, the presence of an ED lost its impact on glycemic control outcomes after the addition of the BMI in the models. Eating psychopathology is frequently observed in patients with T2DM. Among individuals with T2DM, co-morbid ED is associated with a poorer glycemic control in the presence of a higher BMI. The presence of an eating disordered behavior in patients with T2DM seems to have clinical relevance in the usual care of patients with diabetes. Therefore, we recommend eating psychopathology should be routinely assessed in T2DM patients.
机译:饮食行为是与2型糖尿病(T2DM)治疗相关的一个重要方面,可能对血糖控制产生影响。以前的报道显示出患有无序行为的普遍性,特别是2型糖尿病患者的临床样本中的狂犬病患者。然而,关于饮食失调对T2DM血糖和临床控制的影响的结果不一致。本研究的目的是评估一组T2DM患者血糖对照(GC)对血糖对照(GC)的影响。利用DSM-IV的结构化临床访谈和狂欢进食规模,评估70例连续T2DM患者的饮食行为。用空腹血糖(FBG)和糖化血红蛋白(A1C)水平检查GC。此外,评估继发性临床变量,包括体重指数(BMI)和脂质。 Chi-Square和学生的T测试用于比较患者的临床和精神病理学特征,没有ED。为了评估GC与饮食障碍(ED)之间的关系进行线性回归分析,控制BMI。采用了5%的显着性水平。七十七个样品(n?=?54)是女性,50%是肥胖。十四名患者表现出ED,大多是狂暴的饮食障碍(床)。在回归分析中,FBG(β系数?= 47.4(22.3); P?= 0.037)和A1C(β系数?=?1.12(0.57); P?= 0.05)通过存在预测编辑。然而,在模型中添加BMI后,ED的存在对血糖控制结果产生了影响。在T2DM的患者中经常观察到饮食精神病理学。在具有T2DM的个体中,Co-Morbid ED在较高BMI存在下与较差的血糖控制有关。在T2DM患者中存在饮食失调行为似乎在患有糖尿病患者的常规护理中具有临床相关性。因此,我们建议在T2DM患者中常规评估饮食精神病理学。

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