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Pandemic influenza preparedness (PIP) framework: Progress challenges in improving influenza preparedness response capacities in the Eastern Mediterranean Region, 2014–2017

机译:大流行性流感准备(PIP)框架:进展挑战在改善地中海地区东部地中海地区的流感准备响应能力,2014 - 2017年

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Influenza viruses with pandemic potential have been detected in humans in the Eastern Mediterranean Region. The Pandemic Influenza Preparedness (PIP) Framework aims to improve the sharing of influenza viruses with pandemic potential and increase access of developing countries to vaccines and other life-saving products during a pandemic. Under the Framework, countries have been supported to enhance their capacities to detect, prepare for and respond to pandemic influenza. In the Eastern Mediterranean Region, seven countries are priority countries for Laboratory and Surveillance (L&S) support: Afghanistan, Djibouti, Egypt, Jordan, Lebanon, Morocco and Yemen. During 2014–2017, US$ 2.7 million was invested in regional capacity-building and US$ 4.6 million directly in the priority countries. Countries were supported to strengthen influenza diagnostic capacities to improve detection, enhance influenza surveillance systems including sentinel surveillance for severe acute respiratory infection and influenza-like illness, and increase global sharing of surveillance data and influenza viruses. This paper highlights the progress made in improving influenza preparedness and response capacities in the Region from 2014 to 2017, and the challenges faced. By 2017, 18 of the 22 countries of the Region had laboratory-testing capacity, 19 had functioning sentinel influenza surveillance systems and 22 had trained national rapid response teams. The number of countries correctly identifying all influenza viruses in the WHO external quality assurance panel increased from 9 countries scoring 100% in 2014 to 15 countries in 2017, and the number sharing influenza viruses with WHO collaborating centres increased by 75% (from eight to 14 countries); more than half now share influenza data with regional or global surveillance platforms. Seven countries have estimated influenza disease burden and seven have introduced influenza vaccination for high-risk groups. Challenges included: protracted complex emergencies faced by nine countries which hindered implementation of influenza surveillance in areas with the most needs, high staff turnover, achieving timely virus sharing and limited utilization of influenza data where they are available to inform vaccine policies or establish threshold values to measure the start and severity of influenza seasons.
机译:在东地中海地区的人类中检测到流行性潜力的流感病毒。大流行性流感的制备(PIP)框架旨在改善流感病毒与大流行潜力的分享,并在大流行期间增加发展中国家的进入疫苗和其他救生产品。根据该框架,各国得到支持,以提高其检测,准备和对大流行性流感的能力。在东地中海地区,七个国家是实验室和监督的优先国家(L&S)支持:阿富汗,吉布提,埃及,约旦,黎巴嫩,摩洛哥和也门。在2014 - 2017年期间,270万美元被投资于区域能力建设和直接在优先国家的460万美元。各国得到支持加强流感诊断能力,以改善检测,增强流感监测系统,包括Sentinel监测对严重的急性呼吸道感染和流感的疾病,并增加全球监测数据和流感病毒的共享。本文重点介绍了从2014年至2017年改善该地区的流感准备和反应能力的进展,面临的挑战面临。到2017年,该地区22个国家中有18个拥有实验室测试能力,19次运作的哨兵流感监测系统和22次培训了国家快速反应团队。正确识别世卫组织外部质量保证小组中所有流感病毒的国家数量从2014年到15%的9个国家增加到2017年的15个国家,以及与世卫组织合作中心共享流感病毒的数量增加75%(从8到14国家);现在,一半以上与区域或全球监测平台共享流感数据。七个国家估计血型流感疾病负担,七种引入了高风险群体的流感疫苗。挑战包括:九个国家面临的持续复杂紧急情况,其中九个国家受到最多需求,高员工营业额,高级员工营业额,及时的病毒分享和利用流感数据的有限利用,以通知疫苗政策或建立门槛价值衡量流感季节的开始和严重程度。

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