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首页> 外文期刊>Journal of International Medical Research >Cefepime versus Ceftazidime for Treatment of Pneumonia
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Cefepime versus Ceftazidime for Treatment of Pneumonia

机译：头孢心与头孢他犯治疗肺炎

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Consecutive patients with pneumonia, treated with cefepime (n = 66) or ceftazidime (n = 132), were evaluated in a retrospective, observational study. There was no significant difference between the two treatment groups with respect to age, underlying diseases, acute physical and chronic health evaluation score, intensive care unit admission, presence of sepsis, community or hospital acquisition, causative organism, duration of therapy, death, cure or improvement in infection, adverse events, superinfections, presence of vancomycin-resistant enterococcus (VRE) and resistance to therapy. Post-therapy hospitalization (days) and vancomycin co-administration were significantly lower, and time to vancomycin initiation significantly higher, in the cefepime compared with the ceftazidime group. The results suggest a trend towards less resistance on therapy, less VRE, reduced vancomycin use and shorter post-therapy hospitalization in patients treated with cefepime compared with ceftazidime. The clinical outcomes for hospitalized patients treated for serious pneumonia were similar between the two groups.
机译：在回顾性的观察研究中，评估了用头孢吡肟（n = 66）或头孢唑尼（n = 132）治疗的肺炎的连续患者进行评估。两种治疗组关于年龄，潜在的疾病，急性身体和慢性健康评估得分，重症监护单元入院，脓毒症，疾病，致病，治疗持续时间，治愈，治愈的疾病，治愈期或改善感染，不良事件，超育，抗病毒素抗肠病（VRE）的存在和对治疗的抵抗力。治疗后住院治疗（天）和万古霉素共同给药显着降低，与头孢他啶群相比，在头孢噻肟中，时间率明显较低，而万霉素启动显着高得多。结果表明，与头孢他啶相比，对治疗的抗性较少抗性，较少，VRE，减少的万古霉素使用和较短的治疗后疗法住院治疗。两组对治疗的严重肺炎治疗的住院患者的临床结果相似。

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