...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of International Medical Research >Log-transformed B-type natriuretic peptide as a prognostic predictor in patients undergoing cardiovascular surgery
【24h】

Log-transformed B-type natriuretic peptide as a prognostic predictor in patients undergoing cardiovascular surgery

机译：将对象转化的B型Natrietic肽作为经历心血管外科患者的预后预测因子

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Objective This study was performed to explore the association between circulating B-type natriuretic peptide (BNP) and other mortality-related factors in patients undergoing cardiovascular surgery. Methods In this observational study, multilevel linear regression analysis and multilevel survival analysis were performed to measure the log-transformed BNP (lnBNP) value at four time points in 197 patients with 788 repeated data measurements. Effects of the interaction between the time points and the two intervention groups (cardiac surgery and vascular surgery) were also investigated. Six models were evaluated to identify the best fit for the data. Stata/MP? version 14.2 (Stata Corp., College Station, TX, USA) was used to analyze the two-level variance component model fitting. Results There were significant differences in the fixed-effect parameters of lnBNP, such as the time point, age, body mass index, emergency operation, prognostic nutritional index, and estimated glomerular filtration rate. According to the multilevel survival analysis for all-cause death and vascular death, lnBNP significantly differed and was a common prognostic marker. Conclusion As lnBNP increased by 1 point, all-cause death increased 2.07 times and vascular death increased 3.10 times. lnBNP is an important prognostic predictor and quantitative biochemical marker in patients undergoing cardiovascular surgery.
机译：目的是进行本研究以探讨循环B型利钠肽（BNP）与其他死亡率相关因素之间的关联，对经历心血管手术的患者。方法在该观察性研究中，进行多级线性回归分析和多级存活分析，在197例重复数据测量的197例患者的患者中测量了测量对数转化的BNP（LNBNP）值。还研究了时间点与两个干预组之间相互作用的影响（心脏手术和血管手术）。评估六种模型以识别数据的最佳拟合。 stata / mp？版本14.2（Stata Corp.，College Station，TX，USA）用于分析两级方差分量模型配件。结果LNBNP的固定效应参数存在显着差异，如时间点，年龄，体重指数，应急操作，预后营养指数和估计肾小球过滤速率。根据全因死亡和血管死亡的多级存活分析，LNBNP显着差异，是一种常见的预后标志物。结论LNBNP增加1点，全导致死亡增加2.07倍，血管死亡增加3.10倍。 LNBNP是在经历心血管外科患者的重要预测预测因子和定量生化标志。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号