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首页> 外文期刊>Journal of International Medical Research >Brucellar reproductive system injury: A retrospective study of 22 cases and review of the literature
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Brucellar reproductive system injury: A retrospective study of 22 cases and review of the literature

机译：布鲁克拉尔生殖系统损伤：回顾性研究22例，并对文献进行审查

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摘要

Objective We aimed to describe the clinical characteristics and prognosis of 22 patients with Brucella -induced reproductive system injury. Methods We assessed 22 patients with reproductive system injury between 2010 and 2018 at The First Affiliated Hospital of Xinjiang Medical University. Results The disease is predominant in men. Male patients had orchitis, erectile dysfunction, prostatitis, and urethral stricture, while female patients had vaginitis and cervicitis. Some patients had laboratory abnormalities and liver injury. Patients received combination therapy of rifampicin and doxycycline. Doxycycline combined with levofloxacin or moxifloxacin was administered to patients with rifampicin intolerance. All patients had received antibiotic therapy for at least 6 weeks. One patient was lost to follow-up, one patient relapsed because of osteoarthropathy, and one patient had dysuria resulting from chronic prostatitis. The clinical symptoms resolved in the other patients, and the overall patient prognosis was good. Conclusion Clinicians should pay attention to brucellosis-induced reproductive system damage. The two-drug regimen of rifampicin+doxycycline is recommended for these patients. Doxycycline combined with levofloxacin or moxifloxacin should be used in patients with brucellosis-induced reproductive system damage who have rifampicin intolerance. The treatment course should be at least 6 weeks.
机译：目的我们旨在描述22例Brucella-诱导的生殖体系损伤患者的临床特征和预后。方法在新疆医科大学第一次附属医院评估2010年至2018年患有22例生殖系统损伤患者。结果疾病是男性的主要原因。男性患者有睾丸炎，勃起功能障碍，前列腺炎和尿道狭窄，而女性患者患有阴道炎和宫颈炎。有些患者有实验室异常和肝损伤。患者接受了利福平和糖尿环素的联合治疗。将十二胞环素与左氧氟沙星或莫苏西甲酰辛联合给予利福平患者的患者。所有患者均已接受抗生素治疗至少6周。一名患者失去了随访，一名患者因骨脑病而复发，一名患者患有慢性前列腺炎引起的患有困难。在其他患者中解决的临床症状，整体患者预后良好。结论临床医生应注意布鲁氏肿胀诱导的生殖系统损坏。推荐用于这些患者的利福平+强霉素的两种药物方案。强霉素联合左氧氟沙星或莫西沙星应用于患有布鲁克病引起的生殖系统损伤的患者，患有利福平的不耐受性。治疗课程应至少为6周。

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