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首页> 外文期刊>Journal of International Medical Research >Effects of postoperative medical treatment and expectant treatment on dysmenorrhea after conservative laparoscopic surgery for deep-infiltrating endometriosis accompanied by dysmenorrhea
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Effects of postoperative medical treatment and expectant treatment on dysmenorrhea after conservative laparoscopic surgery for deep-infiltrating endometriosis accompanied by dysmenorrhea

机译：术后腹腔镜手术治疗腹腔镜治疗腹腔镜术后术后医疗和预期治疗伴有痢疾治疗子宫内膜异位症

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Objective To compare the efficacy of postoperative adjuvant treatment (gonadotropin-releasing hormone agonists [GnRHas] and oral contraceptives [OCs]) and expectant treatment in preventing recurrent dysmenorrhea following conservative laparoscopic surgery for deep infiltrating endometriosis (DIE) with dysmenorrhea. Methods A prospective cohort study was conducted in Shanghai, China. In total, 147 patients with dysmenorrhea who underwent conservative laparoscopic surgery for DIE were enrolled. Following surgery, patients received either postoperative adjuvant therapy (GnRHa or OCs) for 6 months or expectant treatment according to a shared medical decision-making approach. The primary outcome was the postoperative recurrence of dysmenorrhea. The secondary outcomes included reproductive outcomes and drug-induced side effects. Results The generalized estimating equation analysis illustrated that the visual analog scale for dysmenorrhea was significantly higher in the adjuvant treatment group than in the expectant treatment group. Kaplan–Meier analysis and the log-rank test demonstrated that the cumulative recurrence rate was higher in the expectant treatment group than in the adjuvant treatment group, but no difference was noted between the two hormonal treatments. Similar cumulative 24-month clinical pregnancy rates were observed among the three groups. Conclusions Compared with expectant management, postoperative medical treatment more effectively relieved symptoms and prevented the recurrence of dysmenorrhea.
机译：目的比较术后辅助治疗的疗效（促促丙素 - 释放激素激动剂[Gnrhas]和口服避孕药[OCS]）和预期治疗，防止保守腹腔镜手术治疗腹腔镜治疗腹腔镜的腹腔镜（Die）患有痛经治疗。方法在中国上海进行潜在队列研究。招募了147例患有保守腹腔镜手术的痛经患者。手术后，患者接受术后辅助治疗（GNRHA或OCS）6个月或预期治疗根据共同的医疗决策方法。主要结果是痛经复发。二次结果包括生殖结果和药物诱导的副作用。结果广义估计方程分析表明，佐剂治疗组的痛经的视觉模拟规模显着高于预期治疗组。 Kaplan-Meier分析和对数秩检验表明，预期治疗组中累积复发率高于佐剂治疗组，但两种激素治疗之间没有发现差异。三组中观察到类似累积的24个月临床妊娠率。结论与预期管理相比，术后医疗更有效地缓解了症状并阻止了痛经复发。

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