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Parathyroid mass and patients with nonspecific complaints

机译：甲状旁腺质量和非特异性投诉的患者

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Parathyroid hormone (PTH) is an important hormone possessing critical physiologic functions, including neuromuscular conduction, coagulation and bone mineralisation. Its protein sequence includes 84 amino acids. ~( 1 ) Primary hyperparathyroidism is the most frequent cause of hypocalcaemia, which does not depend on malignancies in patients referred to policlinics. Hypocalcaemia is caused by excessive parathyroid hormone production. Most parathyroid masses are sporadic adenomas (85%), whereas less frequent masses include hyperplasia (10%), multiple adenoma (4%) and carcinoma (1%). ~( 2 – 4 ) Vitamin D deficiency and chronic renal disease are the common causes of secondary hyperparathyroidism. However, specific groups of patients, namely asymptomatic patients referred to policlinics for routine control and patients referred to policlinics with specific symptoms such as fatigue, nausea, loss of appetite and weight loss, require special attention. In these patients, measuring serum Ca is extremely important because several studies revealed that concomitant parathyroid masses and thyroid carcinoma are commonly found in these patients. These patients, who can receive various diagnoses, do not experience improvement of their condition despite treatment. Consequently, their condition deteriorates, and their parathyroid lesions become inoperable. Additionally, these patients experience hypercalcaemic crises because of the delayed diagnosis. Therefore, we want to emphasise the importance of studying serum electrolytes, especially Ca, and using simple imaging modalities such as ultrasonography in patients with indistinct complaints.
机译：甲状旁腺激素（PTH）是具有关键生理功能的重要激素，包括神经肌肉传导，凝血和骨矿化。其蛋白质序列包括84个氨基酸。 〜（1）原发性甲状旁腺功能亢进是低可见的原因，这不依赖于提到政策的患者的恶性肿瘤。低可病症是由过量的甲状旁腺激素生产引起的。大多数甲状旁腺质量是散发性腺瘤（85％），而少量频率差异包括增生（10％），多种腺瘤（4％）和癌（1％）。 〜（2 - 4）维生素D缺乏症和慢性肾病是继发性甲状旁腺功能亢进的常见原因。然而，特定患者群体，即常规控制常规控制患者的无症状患者和患者提到具有特殊症状的患者，如疲劳，恶心，食欲丧失和减肥，需要特别注意。在这些患者中，测量血清CA非常重要，因为有几项研究表明，这些患者常见于伴随的甲状旁腺质量和甲状腺癌。这些患者可以接受各种诊断，尽管治疗，但仍未经历改善其病症。因此，它们的病情恶化，并且它们的甲状旁腺病变不可操作。此外，由于延迟诊断，这些患者会经历高钙危机。因此，我们希望强调研究血清电解质，尤其是Ca的重要性，以及使用模糊抱怨的患者中的超声检查等简单成像模态。

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