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首页> 外文期刊>Journal of International Medical Research >Prevalences and characteristics of cultivable nasal bacteria isolated from preclinical medical students
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Prevalences and characteristics of cultivable nasal bacteria isolated from preclinical medical students

机译：临床前医学生培养鼻细菌的患病率和特征

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Objectives Commensal bacteria in the nasal cavity may act as opportunistic pathogens that cause infections under certain conditions. Screening for commensal bacteria in the nasal cavity may aid in understanding their roles in microbiota balance and preventing potential infections. Methods Nasal samples were collected from healthy preclinical medical students and used to inoculate various bacterial culture media, by means of the WaspLab microbiology automated system. Bacterial colonies were then identified by matrix-assisted laser desorption ionization-time of flight mass spectrometry. Antibiotic resistance phenotypes of Staphylococcus aureus were determined by antibiotic susceptibility tests. Results In total, 549 bacterial strains were isolated from 161 participants. These strains included the following genera: Staphylococcus , Streptococcus , Corynebacterium , Dolosigranulum , Bacillus , Micrococcus , Haemophilus , Neisseria , Moraxella , Pseudomonas , and members of Enterobacteriaceae (e.g., Escherichia , Klebsiella , Citrobacter , Enterobacter , and Serratia ). Approximately 25.5% of students were carriers of S. aureus ; most S. aureus isolates were resistant to penicillin, erythromycin, and clindamycin. The prevalence of methicillin-resistant S . aureus in nasal samples was 4.3%. Conclusions A diverse group of nasal commensal bacteria inhabited our population of healthy volunteers. These data can improve comprehension of the potential roles of these nasal commensal bacteria in regulating microbiota balance and promoting or mitigating potential future infections.
机译：鼻腔中的目标共生细菌可以作为机会主义病原体，导致某些条件下的感染。鼻腔中的共生细菌筛选可能有助于了解他们在微生物群中的作用，并防止潜在的感染。方法采用健康临床前医学生鼻样品，用WASPLAB微生物自动化系统从健康的临床前医学生中收集并用于接种各种细菌培养基。然后通过基质辅助激光解吸电离 - 飞行质谱法鉴定细菌菌落。通过抗生素易感性测试测定金黄色葡萄球菌的抗生素抗性表型。结果总共549种细菌菌株从161名参与者中分离出来。这些菌株包括以下属：葡萄球菌，链球菌，棒状杆菌，嗜睡剂，芽孢杆菌，芽孢杆菌，嗜血杆菌，嗜血杆菌，鼻腔，moraxella，假单胞菌和肠杆菌菌的成员（例如，大肠杆菌，克雷布氏菌，植物杆菌，肠杆菌和肠道）。大约25.5％的学生是金黄色葡萄球菌的载体;大多数S.UUREUS分离物对青霉素，红霉素和克林霉素抵抗。耐甲氧脲患者的患病率。鼻腔中的金黄色葡萄球菌为4.3％。结论多种鼻腔共谋细菌居住在健康志愿者人口。这些数据可以改善这些鼻共和细菌在调节微生物群平衡和促进或减轻潜在未来感染方面的潜在作用的理解。

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