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首页> 外文期刊>Journal of International Medical Research >Update on intensive motor training in spinocerebellar ataxia: time to move a step forward?
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Update on intensive motor training in spinocerebellar ataxia: time to move a step forward?

机译：关于纺纱机构竞技的密集电机训练更新：时间迈向前进的时间？

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Some evidence suggests that high-intensity motor training slows down the severity of spinocerebellar ataxia. However, whether all patients might benefit from these activities, and by which activity, and the underlying mechanisms remain unclear. We provide an update on the effect and limitations of different training programmes in patients with spinocerebellar ataxias. Overall, data converge of the finding that intensive training is still based either on conventional rehabilitation protocols or whole-body controlled videogames (“exergames”). Notwithstanding the limitations, short-term improvement is observed, which tends to be lost once the training is stopped. Exergames and virtual reality can ameliorate balance, coordination, and walking abilities, whereas the efficacy of adapted physical activity, gym, and postural exercises depends on the disease duration and severity. In conclusion, although a disease-modifying effect has not been demonstrated, constant, individually tailored, high-intensity motor training might be effective in patients with degenerative ataxia, even in those with severe disease. These approaches may enhance the remaining cerebellar circuitries or plastically induce compensatory networks. Further research is required to identify predictors of training success, such as the type and severity of ataxia and the level of residual functioning.
机译：有些证据表明，高强度电机训练减缓了纺丝术共济失调的严重程度。但是，所有患者是否可能从这些活动中受益，并通过哪个活动以及潜在机制仍然不明确。我们提供了有关纺丝术患者患者不同培训计划的效果和局限性的更新。总体而言，重症培训仍然基于传统的康复协议或全身控制的视频游戏（“Exergames”）的数据集成。尽管有局限性，但遵循短期改善，一旦训练停止，就往往会丢失。 Exergames和虚拟现实可以改善平衡，协调和行走能力，而适应的身体活动，健身房和姿势锻炼的疗效取决于疾病持续时间和严重程度。总之，虽然尚未证明疾病改性效果，但恒定，单独定制的高强度电机训练可能在退行性共济失调的患者中有效，甚至在具有严重疾病的人中也是有效的。这些方法可以增强剩余的小脑电路或塑料诱导补偿网络。需要进一步的研究来确定培训成功的预测因子，例如共济失调的类型和严重程度和残留功能水平。

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