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首页> 外文期刊>Journal of International Medical Research >Quantifying the number of lymph nodes for examination in breast cancer
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Quantifying the number of lymph nodes for examination in breast cancer

机译：量化乳腺癌检查的淋巴结数

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Objective Examining the correct number of lymph nodes when diagnosing breast cancer invasion is still a problem. This work aimed to develop a qualification model that estimates the possibility of missing nodes and the number of lymph nodes that need to be examined. Methods By analyzing lymph node invasion of 303,760 breast cancer samples with primary tumor stage and the number of examined and positive lymph nodes from the Surveillance, Epidemiology and End Results database using a beta-binomial model, the number of nodes that should be examined was quantified in different stages. Results In general, to reduce the possibility of missing positive nodes to less than 10%, 21 lymph nodes should be examined; thus, the current median of dissected nodes (12) is not adequate. The number of nodes needed to be dissected for stages T1, T2, and T3 are 8, 37, and 87, respectively. Currently, the median number of node dissections for these stages were 12, 13, and 14, respectively. The clinical significance of the nodal staging score was validated with survival information. Conclusion Currently, the number of lymph nodes dissected in breast cancer are excessive for T1 but insufficient for T2 and T3.
机译：目的在诊断乳腺癌入侵时检查正确数量的淋巴结仍然是一个问题。这项工作旨在开发一个资格化模型，估计缺少节点的可能性以及需要检查的淋巴结数量。方法通过分析淋巴结侵袭303,760乳腺癌样品的原发性肿瘤阶段和来自监测，流行病学和最终结果数据库的检测和阳性淋巴结的数量使用β二项式模型，量化了应检查的节点数量在不同的阶段。结果一般来说，为了减少缺阳节点的可能性，应检查21例淋巴结;因此，监察节点（12）的当前中值不足。用于分离T1，T2和T3所需的节点的数量分别为8,37和87。目前，这些阶段的节点分析数分别为12,13和14。节点分期评分的临床意义验证了生存信息。结论目前，在乳腺癌中解剖的淋巴结数量对于T1过量，但T2和T3不足。

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