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首页> 外文期刊>Journal of Medical Radiation Sciences >Evaluation of a mobile C‐arm cone‐beam CT in interstitial high‐dose‐rate prostate brachytherapy treatment planning
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Evaluation of a mobile C‐arm cone‐beam CT in interstitial high‐dose‐rate prostate brachytherapy treatment planning

机译：间质高剂量率前列腺近辐射治疗计划评估移动C形臂锥CT

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Introduction The aim of this study was to evaluate the suitability of using cone‐beam computed tomography (CBCT) obtained with a mobile C‐arm X‐ray fluoroscopy unit as a single modality for planning of high‐dose‐rate (HDR) prostate brachytherapy treatments. Methods The feasibility of using CBCT images obtained using a Siemens Arcadis Orbic 3D mobile C‐arm was evaluated. A retrospective clinical study was undertaken of six participants undergoing HDR prostate brachytherapy. Plans generated using images from a Toshiba Aquilion One LB CT were compared with those generated using CBCT images. After rigid spatial registration, the plans were compared based on various parameters such as dose‐volume histograms, overlap quantities and metrics, and dose constraints. Results Provided they were within the limited field of view, the brachytherapy catheters and fiducial markers were clearly visible in the CBCT images and thus, localisable and identifiable in the treatment planning process. The Siemens CBCT underestimated CT numbers leading to poorer tissue contrast which exacerbated the difficulties in delineation of the target tumour and the surrounding organs at risk. Between CT‐ and CBCT‐based plans, the mean difference of CTV‐ D 90 was 1.58?Gy, CTV‐ V 100 was 12.13%, rectum‐ V 80 was 0.06% and urethra‐ V 120 was ?0.70%. Conclusion It was not feasible to solely utilise the Siemens Arcadis Orbic 3D for HDR prostate brachytherapy treatment planning due to suboptimal organ delineation. However, the methods in this study could be used to evaluate other mobile CBCT imaging devices for feasibility in HDR brachytherapy treatment planning since the results indicated that it may not be necessary to have standard quality CT images for treatment planning.
机译：介绍该研究的目的是评估使用用移动C臂X射线荧光透视单元获得的锥形束计算机断层扫描（CBCT）的适用性，作为用于规划高剂量率（HDR）前列腺近距离放射治疗的单个模态治疗。方法评价使用使用西门子Arcadis轨道3D移动C-臂获得的CBCT图像的可行性。回顾性临床研究是六位参与者接受过HDR前列腺近距离放射治疗的参与者。将使用从东芝Aquilion的图像生成的计划与使用CBCT图像产生的图像进行比较。在刚性空间登记之后，基于各种参数进行比较，例如剂量直方图，重叠数量和度量和剂量约束等各种参数。结果，它们在有限的视野中，在CBCT图像中清晰可见，因此在治疗计划过程中清楚地看到近距离放射治疗导管和基准标记。西门子CBCT低估了CT编号，导致较差的组织造影，这加剧了靶肿瘤划分的困难和风险的周围器官。在基于CT和CBCT的计划之间，CTV-D 90的平均差异为1.58？GY，CTV-V 100为12.13％，直肠-V 80为0.06％，尿道-V 120是β0.70％。结论由于次优器官描绘，仅利用西门子Arcadis Orbic 3D对HDR前列腺近距离放射治疗计划进行的不可行。然而，本研究中的方法可用于评估其他移动CBCT成像装置，以便在HDR近距离放射治疗计划中的可行性，因为结果表明，可能没有必要具有用于治疗计划的标准质量CT图像。

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