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首页> 外文期刊>Journal of oncology >Treatment of Spinal Metastases with Epidural Cord Compression through Corpectomy and Reconstruction via the Traditional Open Approach versus the Mini-Open Approach: A Multicenter Retrospective Study
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Treatment of Spinal Metastases with Epidural Cord Compression through Corpectomy and Reconstruction via the Traditional Open Approach versus the Mini-Open Approach: A Multicenter Retrospective Study

机译:通过传统开放方法与迷你开放方法的心态和重建对脊髓转移脊髓转移率的处理与迷你开放方法:多中心回顾性研究

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Patients with metastatic epidural spinal cord compression (MESCC) often need surgical intervention due to pain, neurological deficits, and spinal instability. Spinal disease is commonly treated via the minimally invasive mini-open approach. However, few studies have evaluated MESCC treatment via mini-open approach. The present study compared the traditional open approach versus the mini-open approach for thoracolumbar MESCC. A cohort of 209 consecutive patients who were diagnosed with thoracolumbar metastases and underwent corpectomy and polymethylmethacrylate reconstruction from 2010 to 2016 was retrospectively identified. Traditional open surgery was performed in 113 patients (open group; mean age 57.7 years), while 96 patients underwent mini-open surgery (mini-open group; mean age 54.3 years). Patients were followed up for 24 months or until death. The baseline characteristics of both groups were similar. The most common origin of the primary lesion was the lung (37.3%), hematological system (22.0%), and kidney (15.8%). Surgery effectively achieved pain relief, restored neurological function, and improved quality of life in both groups. The mini-open group was superior to the open group regarding estimated blood loss, blood transfusion, hospital stay, complications, and pain score. While the mini-open group had a longer operation time than the open group, the two groups had similar improvements in the Frankel grade and Karnofsky functional score. The 30-day mortality rate tended to be higher in the open group (5.3%) than the mini-open group (2.1%) without significance. The 24-month survival rate was similar in both groups (26.5% versus 26.0%). In conclusion, surgery improved pain, function, and quality of life in patients with MESCC. The mini-open approach resulted in less estimated blood loos, less blood transfusion, and shorter hospitalization than the traditional open approach, while both methods had similar mortality and morbidity rates. Thus, the mini-open approach may be more beneficial than the traditional approach for MESCC.
机译:患有转移性硬膜外脊髓压缩(MESCC)的患者通常需要由于疼痛,神经缺陷和脊柱不稳定性而需要手术干预。脊柱疾病通常通过微创迷你开放方法治疗。然而,很少有研究通过迷你开放方法评估了MESCC治疗。本研究比较了传统的开放方法与胸瘤MESCC的迷你开放方法。回顾性鉴定了从2010年至2016年诊断出患有胸腰椎转移和接受的心甲酰胺和聚甲基丙烯酸甲酯重建的209名连续患者的队列。传统的开放手术在113名患者中进行(开放组;平均57.7岁),而96名患者接受迷你外开放(迷你开放组;平均54.3岁)。患者随访24个月或直至死亡。两组的基线特征是相似的。最常见的原始病变的起源是肺(37.3%),血液系统(22.0%)和肾脏(15.8%)。手术有效地实现了疼痛缓解,恢复的神经功能,以及两组的生活质量。迷你开放组优于开放组关于估计损伤,输血,住院住宿,并发症和疼痛评分。虽然迷你开放集团的运营时间比开放组更长,但两组在Frankel级和Karnofsky功能得分中具有相似的改进。开放组的30天死亡率趋于比迷你开放组(2.1%)更高。两组的24个月存活率相似(26.5%,而26.0%)。总之,手术改善了MESCC患者的疼痛,功能和生活质量。迷你开放的方法导致血液润肺较少,输血较少,住院时间较短,而这两种方法都具有相似的死亡率和发病率。因此,迷你开放方法可能比MESCC的传统方法更有益。

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