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首页> 外文期刊>Journal of Ophthalmology >Therapeutic Effect of Intense Pulsed Light (IPL) Combined with Meibomian Gland Expression (MGX) on Meibomian Gland Dysfunction (MGD)
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Therapeutic Effect of Intense Pulsed Light (IPL) Combined with Meibomian Gland Expression (MGX) on Meibomian Gland Dysfunction (MGD)

机译：激烈脉冲光（IPL）与Meibomian腺体表达（MGX）联合的治疗效果（MGD）（MGD）

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Purpose. Our study aimed to evaluate the efficiency of intense pulsed light (IPL) combined with meibomian gland expression (MGX) in treating meibomian gland dysfunction (MGD). Methods. This study was a prospective interventional study. A total of 53 patients were included in the study and received a series of three treatments at an interval of 3-4 weeks. Follow-up examinations were completed 4 weeks after the last treatment. The Ocular Surface Disease Index (OSDI) questionnaire, tear meniscus height (TMH), tear break-up time (TBUT), slit-lamp examinations, and in vivo confocal microscopy (IVCM) were recorded before and after treatment. Additionally, an artificial intelligence automated software program was applied in our study for corneal nerve analysis. Results. The OSDI score was significantly reduced after the IPL treatment compared with baseline (P0.001). Meibomian gland assessment scores, including meibum quality and expressibility, eyelid margin abnormalities, and corneal staining, significantly decreased after treatment (P0.05). Moreover, the corneal nerve fiber length (CNFL) significantly increased after the treatment (P0.001). Conclusion. Intense pulsed light (IPL) combined with MGX is an effective treatment for MGD, and neurotrophism could be one of the mechanisms of IPL.
机译：目的。我们的研究旨在评估激烈的脉冲光（IPL）与Meibomian腺体表达（MGX）相结合治疗Meibomian Gland功能障碍（MGD）。方法。本研究是一个前瞻性介入研究。该研究共纳入53名患者，并在3-4周的间隔接受一系列三种治疗方法。在最后一次治疗后4周完成后续检查。在治疗之前和之后，记录了眼部表面疾病指数（OSDI）调查问卷，撕裂半月形高度（TMH），撕裂分发时间（TBUT），粘接灯检查和体内共聚焦显微镜（IVCM）。此外，在我们的角膜神经分析研究中应用了人工智能自动化软件程序。结果。 IPL治疗与基线相比（P <0.001）后，OSDI评分显着降低。 Meibomian Gland评估评分，包括梅比品质和表现性，眼睑缘异常和角膜染色，治疗后显着降低（P <0.05）。此外，治疗后角膜神经纤维长度（CNFL）显着增加（P <0.001）。结论。激烈的脉冲光（IPL）与MGX结合是对MGD的有效治疗，神经营养性可以是IPL的机制之一。

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