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首页> 外文期刊>Journal of Pharmacy and Bioallied Sciences >Comparison of Antibacterial Effect of Calcium Hydroxide Combined With Chlorhexidine and Povidone-Iodine Against Enterococcus faecalis in Dentinal Tubules of Human Incisors: An In Vitro Comparative Study
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Comparison of Antibacterial Effect of Calcium Hydroxide Combined With Chlorhexidine and Povidone-Iodine Against Enterococcus faecalis in Dentinal Tubules of Human Incisors: An In Vitro Comparative Study

机译：氢氧化钙与氯己酮和聚维酮 - 碘对人体牙髓牙本质小管肠球菌和POVIDONE-碘的抗菌作用的比较：体外比较研究

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It has been found that the microorganism behind the failure of root-filled teeth is Enterococcus faecalis, which shows resistance to most of the intra-canal medicaments. Therefore, the purpose of this study was to evaluate the antibacterial efficacy of three intra-canal medications—calcium hydroxide with saline, combinations of calcium hydroxide with 2% chlorhexidine (CHX), and calcium hydroxide with 5% povidone-iodine—against E. faecalis in dentinal tubules of human incisors.Materials and Methods:Forty permanent maxillary central incisors were made into standardized segments and infected with E. faecalis. They were treated with a paste made of calcium hydroxide and 2% CHX, calcium hydroxide and 5% povidone-iodine, and calcium hydroxide and saline for 1 week. Dentinal shavings collected from the canal were suspended in thioglycollate broth solution and spread on brain heart infusion agar. Colony-forming units (CFUs) were enumerated and the CFU per milligram of dentin was calculated. The pH of the medicaments used was measured with the help of pH meter.Results:The results showed that the paste made from calcium hydroxide and 2% CHX was significantly more effective than that made from calcium hydroxide and povidone-iodine, and calcium hydroxide and saline. The addition of CHX or povidone-iodine did not affect the alkalinity of calcium hydroxide.Conclusion:This study concludes that Ca(OH)2 + 2% CHX are effective against E. faecalis. Combinations of calcium hydroxide and 5% povidone-iodine showed better antibacterial effect than calcium hydroxide and saline. Ca(OH)2 + saline was ineffective against E. faecalis.
机译：已经发现，根填充牙齿失败背后的微生物是肠球菌粪便，这表明对大多数管内药物的抵抗力。因此，本研究的目的是评估三种管内内药物 - 氢氧化钙的抗菌效果 - 盐水，氢氧化钙与2％氯己定（CHX）的组合，以及具有5％POVIDONE-碘 - 对E的氢氧化钙。粪便牙本质小管中的人体门牙。材料和方法：将40个永久上颌中央门牙进行标准化的细分，并感染了E.粪便。将它们用氢氧化钙和2％CHX，氢氧化物和5％POVIDONE-碘和氢氧化钙和盐水处理过的糊剂处理1周。从运河收集的牙本质削片被悬浮在噻糖基肉汤溶液中，并在脑心脏输注琼脂上传播。枚举形成单位（CFU）并计算每毫林的牙本质的CFU。使用pH计的帮助测量使用的药物的pH。结果表明，结果表明，由氢氧化钙和2％CHX制成的糊剂比由氢氧化钙和聚维酮 - 碘和氢氧化钙制成的更有效。盐水。加入CHX或POVIDONE-碘不影响氢氧化钙的碱度。结论：该研究得出结论，CA（OH）2 + 2％CHX对E.粪便有效。氢氧化钙和5％povidone-碘的组合显示比氢氧化钙和盐水更好的抗菌效果。 Ca（OH）2 +盐水对E. Faecalis无效。

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