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首页> 外文期刊>Journal of the International Society of Sports Nutrition >Effects of daily ingestion of sodium bicarbonate on acid-base status and anaerobic performance during an altitude sojourn at high altitude: a randomized controlled trial
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Effects of daily ingestion of sodium bicarbonate on acid-base status and anaerobic performance during an altitude sojourn at high altitude: a randomized controlled trial

机译：高海拔高度索税期间碳酸氢钠对酸碱状态和厌氧性能的影响：随机对照试验

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The present study investigated the effects of chronic sodium bicarbonate (NaHCO3) ingestion on a single bout of high-intensity exercise and on acid-base balance during 7-day high-altitude exposure. Ten recreationally active subjects participated in a pre-test at sea level and a 7-day hiking tour in the Swiss Alps up to 4554?m above sea level. Subjects received either a daily dose of 0.3?g/kg NaHCO3 solution (n?=?5) or water as a placebo (n?=?5) for 7?days. Anaerobic high-intensity exercise performance was assessed using the portable tethered sprint running (PTSR) test under normoxic and hypoxic conditions (3585?m). PTSR tests assessed overall peak force, mean force, and fatigue index. Blood lactate levels and blood gas parameters were assessed pre- and post-PTSR. Urinary pH and blood gas parameters were further analyzed daily at rest in early morning samples under normoxic and hypoxic conditions. There were no significant differences between the bicarbonate and control group in any of the PTSR-related parameters. However, urinary pH (p?=?0.003, ηp2?=?0.458), early morning blood bicarbonate concentration (p??0.001, ηp2?=?0.457) and base excess (p?=?0.002, ηp2?=?0.436) were significantly higher in the bicarbonate group compared with the control group under hypoxic conditions. These results indicate that oral NaHCO3 ingestion does not ameliorate the hypoxia-induced impairment in anaerobic, high-intensity exercise performance, represented by PTSR-related test parameters, under hypobaric, hypoxic conditions, but the maximal performance measurements may have been negatively affected by other factors, such as poor implementation of PTSR test instructions, pre-acclimatization, the time course of hypoxia-induced renal [HCO3?] compensation, changes in the concentrations of intra- and extracellular ions others than [H+] and [HCO3?], or gastrointestinal disturbances caused by NaHCO3 ingestion. However, chronic NaHCO3 ingestion improves blood bicarbonate concentration and base excess at altitude, which partially represent the blood buffering capacity.
机译：本研究研究了在7天高空暴露期间对单个高强度运动和酸碱平衡的单一Bout的慢性碳酸氢钠（NaHCO 3）摄取的影响。十个娱乐活动受试者参加了海平面的预测和瑞士阿尔卑斯山的7天徒步旅行，高达4554米以上海平面。受试者收到每日0.3〜kg NaHCO 3溶液（N？=Δ5）或水作为安慰剂（n？=？5）7？天。使用常氧和缺氧条件下的便携式束缚冲刺（PTSR）测试评估厌氧高强度运动性能（3585μm）。 PTSR测试评估了总峰值力，平均力和疲劳指数。评估血液乳酸水平和PTSR后的血液气体参数。每天在常氧和缺氧条件下在清晨样品中进一步分析尿pH和血气参数。在任何PTSR相关参数中，碳酸氢盐和对照组之间没有显着差异。但是，尿pH（p？= 0.003，ηp2？= 0.458），清晨血液碳酸氢盐浓度（p？<〜0.001，ηp2？= 0.457）和碱过量（p？= 0.002，ηp2？=？在缺氧条件下与对照组相比，碳酸氢盐组的0.436）显着高。这些结果表明，口服NaHCO 3摄入不改善受到厌氧，高强度运动性能的缺氧诱导的缺氧损伤，该表现在低次要的缺氧条件下，但最大的性能测量可能对其他物质产生负面影响因素，如差的PTSR测试指令的差，素食预期，缺氧诱导的肾脏[HCO3吗？]补偿，浓度的浓度和细胞外离子的浓度而不是[H +]和[HCO3？]，或由NaHCO3摄入引起的胃肠道紊乱。然而，慢性NaHCO 3摄入改善了血液碳酸氢盐浓度和高度的基础，部分地代表血液缓冲能力。

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