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首页> 外文期刊>Journal of Transfusion >Comparison of Epidemiological Methods for Estimation of Hepatitis B Incidence and Residual Risk for Blood Donors in Southern Brazil
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Comparison of Epidemiological Methods for Estimation of Hepatitis B Incidence and Residual Risk for Blood Donors in Southern Brazil

机译：巴西南部乙型肝炎发病率估算流行病学方法的比较

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Background and Objective. The objective of this work was to compare three methods for estimating hepatitis B virus (HBV) incidence and residual risk. Methods. Computerized blood donor records in southern Brazil were examined for the period 2004–2006. The methods for estimating HBV incidence included stand-alone HBsAg, HBsAg yield method, and an extension of the latter which added recent anti-HBc seroconversions as incident HBV cases. Results. HBV incidences for the above methods were 9.91, 20.09, and 22.93 per 100000 repeat donors, respectively. In the same order, corresponding residual risks were 1  62482, 1  30821, and 1  47559, respectively. First-time donors had 52 higher HBV incidence compared to repeat donors. Conclusion. Although the three methods compared produced overlapping 95% confidence intervals, their variation was considerably lower for the method which included recent anti-HBc seroconversions. First-time donors are primary cause for concern regarding HBV transmission via blood transfusion in southern Brazil.
机译：背景和目标。这项工作的目的是比较三种方法来估算乙型肝炎病毒（HBV）发病率和残余风险。方法。在2004 - 2006年期间审查了巴西南部的计算机化献血者记录。估计HBV发病率的方法包括独立的HBsAg，HBsAg产量方法，以及后者的延伸，其近期的抗HBC血清Versions作为事件HBV病例。结果。上述方法的HBV发病率分别为9.91,20.09和22.93每100000个重复捐助者。在相同的顺序中，相应的残留风险分别为1 62482,130821和1 47559。与重复供体相比，首次供体具有52个HBV入射率。结论。虽然三种方法比较了重叠的95％置信区间，但对于包括最近的抗HBC血清血管频率的方法，它们的变化显着降低。首次捐助者是通过巴西南部通过输血的HBV传播令的主要原因。

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