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Simultaneous electrochemical detection of levodapa, paracetamol and l-tyrosine based on multi-walled carbon nanotubes

机译:基于多壁碳纳米管的左旋蛇,扑热息痛和L-酪氨酸的同时电化学检测

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Herein multi-walled carbon nanotubes (MWCNTs) were processed by ultrasonication and freeze-drying method. The morphology of the processed MWCNTs was examined by scanning electron microscopy. An original electrochemical sensor for the simultaneous detection of levodapa (LD), paracetamol (PA) and L -tyrosine (Tyr) was developed by dropcasting a mixture of processed MWCNTs and Nafion on a glassy carbon electrode. The as-prepared sensor was studied by cyclic voltammetry and differential pulse voltammetry. The peak currents of LD, PA and Tyr significantly increased compared to those obtained at bare glassy carbon electrodes or unprocessed MWCNTs modified electrodes. The peaks of LD, PA and Tyr were well-defined and obviously separated from each other. The linear ranges for detection of LD, PA and Tyr were 2.0–300.0, 2.0–180.0, and 2.0–120.0 μM, with a detection limit of 0.6, 0.5 and 0.8 μM (S/N = 3), respectively. Finally, the sensor was applied to detect LD, PA and Tyr in serum samples, and the results were satisfactory.
机译:这里通过超声波和冷冻干燥方法处理多壁碳纳米管(MWCNT)。通过扫描电子显微镜检查处理的MWCNT的形态。通过将加工的MWCNT和Nafion的混合物脱落在玻璃状碳电极上,通过将加工的MWCNT和Nafion的混合物进行同时检测的原始电化学传感器。通过循环伏安法和差分脉冲伏安法研究了AS制备的传感器。与在裸玻璃碳电极或未加工的MWCNT改性电极中获得的那些相比,LD,PA和Tyr的峰值电流显着增加。 LD,Pa和Tyr的峰是明确的,显然彼此分开。用于检测LD,PA和Tyr的线性范围为2.0-300.0,2.0-180.0和2.0-120.0μm,检出限为0.6,0.5和0.8μm(s / n = 3)。最后,将传感器应用于血清样品中的LD,Pa和Tyr,结果令人满意。

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