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首页> 外文期刊>RSC Advances >Comparative investigations of in vitro and in vivo bioactivity of titanium vs. Ti–24Nb–4Zr–8Sn alloy before and after sandblasting and acid etching
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Comparative investigations of in vitro and in vivo bioactivity of titanium vs. Ti–24Nb–4Zr–8Sn alloy before and after sandblasting and acid etching

机译：钛对钛钛钛和钛 - 24NB-4ZR-8SN合金体内体内生物活性的比较研究及酸蚀刻

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To avoid the failure of clinical surgery due to “stress shielding” and the loosening of an implant, a new type of alloy, Ti–24Nb–4Zr–8Sn (TNZS), with a low Young's modulus acted as a new implant material in this work. Meanwhile, the surface characteristics, MC3T3-E1 cell behavior and in vivo osseointegration of the titanium and TNZS before and after sandblasting and acid etching were studied comparatively. TNZS and Ti had the same microstructure based on the transmission electron microscopy results. Meanwhile, the TNZS alloy had a lower Young's modulus and surface nanohardness compared with pure titanium. However, the corrosion resistance of Ti was better than that of the TNZS sample in simulated body fluid solution. In addition, the TNZS alloy after sandblasting and acid etching (SLATNZS) had excellent cell adhesion, proliferation, differentiation, ALP activity and in vivo osseointegration ability such as there being almost no soft tissue as compared with other implants. Based on the current results, the new type of Ti–24Nb–4Zr–8Sn alloy showed good potential and promising application prospects in its biochemical aspects.
机译：为了避免由于“应力屏蔽”和植入物的松动，临床手术的失败，一种新型合金，Ti-24nb-4zr-8sn（TNZs），具有低杨氏模量的作用为新的植入物质工作。同时，研究了钛和TNZ的表面特征，MC3T3-E1细胞行为和钛和TNZ的体内渗透，并进行了比较。 TNZS和Ti基于透射电子显微镜结果具有相同的微观结构。同时，与纯钛​​相比，TNZS合金具有较低的杨氏模量和表面纳米型。然而，Ti的耐腐蚀性优于模拟体液液中TNS样品的耐腐蚀性。此外，喷砂和酸蚀刻（SLATNZS）之后的TNZS合金具有优异的细胞粘附，增殖，分化，ALP活性和体内渗透能力，例如与其他植入物相比几乎没有软组织。基于当前结果，新型的TI-24NB-4ZR-8SN合金在其生化方面显示出良好的潜力和有希望的应用前景。

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