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Biomedical applications of dendritic fibrous nanosilica (DFNS): recent progress and challenges

机译:树突式纤维纳米碱(DFNS)的生物医学应用:最近的进展与挑战

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Dendritic fibrous nanosilica (DFNS), with multi-component and hierarchically complex structures, has recently been receiving significant attention in various fields of nano-biomedicine. DFNS is an emerging class of mesoporous nanoparticles that has attracted great interest due to unique structures such as open three-dimensional dendritic superstructures with large pore channels and highly accessible internal surface areas. This overview aims to study the application of DFNS towards biomedical investigations. This review is divided into four main sections. Sections 1–3 are related to the synthesis and characterization of DFNS. The biomedical potential of DFNS, such as cell therapy, gene therapy, immune therapy, drug delivery, imaging, photothermal therapy, bioanalysis, biocatalysis, and tissue engineering, is discussed based on advantages and limitations. Finally, the perspectives and challenges in terms of controlled synthesis and potential nano-biomedical applications towards future studies are discussed.
机译:具有多组分和分层复杂结构的树突纤维纳米碱(DFN)最近在纳米生物医学的各个领域中得到了重大关注。 DFN是一种新出现的介孔纳米颗粒,由于独特的结构,如具有大孔通道的开放三维树突式上展等独特结构,吸引了巨大的兴趣和高度可接近的内表面区域。此概述旨在研究DFN迈向生物医学调查的应用。该评论分为四个主要部分。第1-3节与DFN的合成和表征有关。基于优点和限制,讨论了DFN的生物医学潜力,如细胞疗法,基因治疗,免疫治疗,药物递送,成像,光热疗,生物分析,生物分析和组织工程。最后,讨论了对受控合成和潜在纳米生物医学应用方面的观点和挑战,是未来研究的。

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