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Simultaneous electrochemical detection of dopamine and epinephrine in the presence of ascorbic acid and uric acid using a AgNPs–penicillamine–Au electrode

机译:使用Agnps-penicillamine-au电极在存在抗坏血酸和尿酸中的多巴胺和肾上腺素的同时电化学检测

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A highly selective and sensitive electrochemical sensor, AgNPs–penicillamine–Au, was developed for the simultaneous detection of dopamine (DA) and epinephrine (EP) in the presence of a high concentration of ascorbic acid (AA) and uric acid (UA). Microscopy and voltammetry techniques were used for the characterization of the modified electrode. Chronoamperometry was used for the determination of DA and EP in the linear range of 0.1 to 100.0 μM with detection limits of 0.2 nM and 0.5 nM, respectively. The simultaneous determination of DA, EP, AA and UA was achieved by using differential pulse voltammetry. The proposed sensor was successfully applied for the simultaneous determination of DA and EP in human blood sample with excellent recovery.
机译:开发了一种高度选择性和敏感的电化学传感器AgNPS-Penicillamine-Au,用于在高浓度的抗坏血酸(AA)和尿酸(UA)存在下同时检测多巴胺(DA)和肾上腺素(EP)。显微镜和伏安法技术用于修饰电极的表征。计时率测定用于在0.1至100.0μm的线性范围内测定DA和EP,其检测限为0.2nm和0.5nm。通过使用差分脉冲伏安法实现DA,EP,AA和UA的同时测定。所提出的传感器成功地应用于具有优异回收率的人血样同时测定DA和EP。

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