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One-pot synthesis of CuFeO2 nanoparticles capped with glycerol and proteomic analysis of their nanocytotoxicity against fungi

机译:用甘油和蛋白质组学分析对真菌的甘油和蛋白质组学分析的单壶合成

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One-pot synthesis of cuprous ferrite (CuFeO _(2) ) nanoparticles modified with glycerol (glycerol@CuFeO _(2) NPs) using oligol and reducing agent was reported. The antifungal activities of the nanoparticles for Candida utilis using matrix assisted laser desorption/ionization mass spectrometry (MALDI-MS) are also reported. Glycerol@CuFeO _(2) NPs are synthesized via hydrothermal method and characterized using TEM, SEM, EDX, XRD, FTIR, DLS, and zeta potential. The data revealed that glycerol@CuFeO _(2) NPs show an efficient ability to degrade contaminants, such as fungi in the aquatic environment. The proteomic analysis of the pathogenic fungus upon addition of different concentrations of glycerol@CuFeO _(2) NPs and different incubation times reveals the degradation of high molecular weight protein to small proteins or peptides.
机译:用甘油(甘油@ CuFeo _(2)NPS的亚克酸亚铜(CuFeO _(2))纳米颗粒合成使用寡醇和还原剂。还报道了使用基质辅助激光解吸/电离质谱(MALDI-MS)的念珠菌的纳米颗粒的抗真孔的抗真菌菌活性。甘油@ CuFeo _(2)NPS通过水热法合成,并使用TEM,SEM,EDX,XRD,FTIR,DLS和Zeta电位进行了特征。数据显示,甘油@ cufeo _(2)NPS显示出有效降解污染物的能力,例如水生环境中的真菌。在加入不同浓度的甘油@ CuFeo _(2)NPS和不同孵育时间后,致病真菌的蛋白质组学分析显示出高分子量蛋白的降解到小蛋白质或肽。

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