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A quick, mild and efficient bromination using a CFBSA/KBr system

机译:使用CFBSA / KBR系统快速,轻度和高效的溴化

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Bromination is a fundamental transformation in organic chemistry and brominated compounds as building blocks are of paramount importance in organic synthesis. In our study, we have developed an efficient method of bromination by using a CFBSA/KBr system at room temperature in a short reaction time. Notably, this approach has been proven to be applicable to a range of substrates including 1,3-diketones and β-keto esters, phenols, aromatic amines and heteroarenes with good to excellent yields.
机译:溴化是有机化学和溴化化合物作为构建块的基本转化在有机合成中至关重要。在我们的研究中,我们在短反应时间内在室温下使用CFBSA / KBR系统开发了一种有效的溴化方法。值得注意的是,已经证明这种方法适用于一系列基材,包括1,3-二酮和β-酮​​酯,酚,芳族胺和杂种物,其具有良好的产率。

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