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An ESIPT based fluorescent probe for imaging hydrogen sulfide with a large turn-on fluorescence signal

机译:用于成像硫化氢的基于氨基磷荧光探针,具有大的开启荧光信号

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摘要

Through an intramolecular nucleophilic substitution reaction and ESIPT mechanism, we designed and synthesized a fluorescent hydrogen sulfide probe with a large turn on fluorescence signal (400-fold). The new probe exhibits high selectivity, good membrane-permeability and is suitable for the visualization of exogenous and endogenous hydrogen sulfide in living cells.
机译:通过分子内的亲核代替反应和ESIPT机理,我们设计并合成了荧光硫化氢探针,荧光信号(400倍)。新探针具有高选择性,良好的膜渗透性,并且适用于活细胞中外源和内源性硫化氢的可视化。

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