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Textile/Al2O3–TiO2 nanocomposite as an antimicrobial and radical scavenger wound dressing

机译:纺织/ Al2O3-TiO2纳米复合物作为抗微生物和自由基清除剂伤口敷料

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Improving the antimicrobial activity and radical scavenging ability of a textile-based nanocomposite (textile/TiO _(2) , textile/Al _(2) O _(3) /TiO _(2) , textile/Al _(2) O _(3) and textile/Al _(2) O _(3) –TiO _(2) bimetal oxide nanocomposite) is the key issue in developing a good and flexible wound dressing. In this work, flexible textile attached with Al _(2) O _(3) –TiO _(2) nanoparticles was prepared by dipping the textile in a suspension containing Al _(2) O _(3) –TiO _(2) nanoparticles (150 mmol l ~(?1) ). The mean radical scavenging ability for textile/TiO _(2) , textile/Al _(2) O _(3) /TiO _(2) , textile/Al _(2) O _(3) and textile/Al _(2) O _(3) –TiO _(2) bimetal oxide nanocomposites as measured by liquid ultraviolet visible spectroscopy (UV-Vis) coupled with dependence formula was 0.2%, 35.5%, 35.0% and 38.2%, respectively. Based on the X-ray diffraction (XRD) patterns, the preface reactive oxygen species (ROS) scavenging ability shown by the textile/Al _(2) O _(3) –TiO _(2) bimetal oxide nanocomposite is most probably caused by the crystal structure concluding in a corundum-like structure, with Al ~(3+) ions filling the octahedral sites in the lattice. Increased antimicrobial activity measured by optical density at 600 nm recorded for textile/Al _(2) O _(3) –TiO _(2) bimetal oxide nanocomposites showed better interaction between Al _(2) O _(3) and TiO _(2) nanoparticles. This good interaction is expected to lead to better antimicrobial and radical scavenging ability as shown by the E. coli and human skin fibroblast (HSF) cytotoxicity tests, respectively.
机译:提高纺织基纳米复合材料的抗微生物活性和自由基清除能力(纺织/ TiO _(2),纺织/ Al _(2)O _(3)/ TiO _(2),纺织/ Al _(2)O. _(3)和纺织/ Al _(2)O _(3)-tio _(2)二金属氧化物纳米复合材料是开发良好和柔性伤口敷料的关键问题。在这项工作中,通过将纺织品浸入含有Al _(2)O _(3)-ti_(2的悬浮液中,制备柔性纺织品α-(2)纳米颗粒。(2 )纳米颗粒(150mmol L〜(α1))。纺织/ TiO_(2),纺织/α(2)O _(3)/ TiO _(2),纺织/α(2)o _(3)和纺织/ al _ (2)o _(3)-tio _(2)通过液体紫外可见光谱(UV-VI)测量的二氧化二金属氧化物纳米复合材料分别与依赖性公式偶联为0.2%,35.5%,35.0%和38.2%。基于X射线衍射(XRD)图案,纺织品/ Al _(2)O _(3)-TiO _(2)二金属氧化物纳米复合材料所示的前言活性氧物质(ROS)清除能力最大可能引起通过晶状体结构在核状结构中结束,用Al〜(3+)离子填充晶格中的八面体位点。通过在纺织品/ Al _(2)O _(3)-TiO _(2)二金属氧化物纳米复合材料中记录的600nm以600nm的光密度测量的增加的抗微生物活性在Al _(2)O _(3)和TiO _之间具有更好的相互作用。 (2)纳米粒子。预计该良好的相互作用将导致抗微生物和激进的清除能力,如大肠杆菌和人体皮细胞(HSF)细胞毒性试验所示。

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