Neurons are thought to primarily rely on glucose to fuel mitochondrial metabolism. In this issue, Divakaruni et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201612067) show that neurons are also happy to use glutamate. When neurons use this neurotransmitter, its concentration drops, thus protecting against glutamate-induced excitotoxic stress.
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机译:神经元被认为主要依赖于葡萄糖来促进线粒体代谢。在这个问题上,Divakaruni等。 (2017. J. Cell Biol。https://doi.org/10.1083/jcb.201612067)显示神经元也很乐意使用谷氨酸。当神经元使用这种神经递质时,其浓度下降,从而保护抑制谷氨酸诱导的兴奋毒性应激。
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