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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Clinical Manifestations and Associated Complications of Scrub Typhus in Odisha, India
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Clinical Manifestations and Associated Complications of Scrub Typhus in Odisha, India

机译：印度Otisha的临床表现与磨砂伤寒的关联并发症

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Scrub typhus is a re-emerging illness in the South-East Asia and other parts of the world caused by Orientia tsutsugamushi , which is a mite-borne bacterium belonging to the Rickettsiaceae family. It has varied clinical manifestations and affects multiple organ systems. In Asia, about 1 million new cases are identified annually.Aim: The aim was to conduct a retrospective study to observe the clinical profile and complications of scrub typhus in South-Eastern India.Materials and Methods: Clinical data of 240 patients who were 18 years of age or above, admitted in the Department of Internal Medicine and diagnosed with scrub typhus by means of IgM ELISA was collected. Demographic profile, clinical signs and symptoms, laboratory parameters, co-infections and complications were reviewed. Statistical analyses were performed using Chi-square test.Results: Majority of the patients were males, between the age of 18-29 years and lived in rural areas. Forty-three (17.9%) patients were admitted in the ICU and the remaining in wards. Sixty-nine (28.8%) patients had consolidation and 11 (4.6%) had Acute Respiratory Distress Syndrome (ARDS). Twenty-one (8.8%) patients had jaundice and 76 (31.7) had hepatomegaly. Twenty-one (8.8%) patients had meningo-encephalitis and 18 (7.5%) had acute kidney injury. Twelve (5%) patients had co-infection with dengue and 8 (3.3%) had malaria.Conclusion: This study shows wide and varied presentation of scrub typhus infection along with the course of the disease and response to the treatment. The diagnostic clues such as fever, eschar, rashes, lymphadenopathy should be kept in mind by a primary care physician as early recognition and treatment can prevent its dangerous complications and reduce the mortality due to the disease. Occurrence of co-infections should also be kept in mind for better management of the patient.
机译：磨砂动卵体是东南亚和世界其他地区的重新出现的疾病，由东方Tsutsugamushi造成的，这是一个属于Rickettsiaceae家族的螨虫细菌。它具有各种临床表现，并影响多个器官系统。在亚洲，每年均确定约100万件新病例。目的：目的是进行回顾性研究，观察印度东南部的临床剖面和磨砂动鼠的并发症。材料和方法：临床数据在18岁或以上的240名患者中，在内科部承认并通过IGM ELISA诊断患有磨砂动脉毛刺。综述了人口统计概况，临床症状和症状，实验室参数，共感染和并发症。使用Chi-Square测试进行统计分析。结果：大多数患者是男性，18-29岁之间，生活在农村。在ICU和剩余的病房中录取了四十三（17.9％）患者。六十九（28.8％）患者综合，11例（4.6％）患有急性呼吸窘迫综合征（ARDS）。二十一（8.8％）患者有黄疸，76名（31.7）患有肝脏肿大。二十一（8.8％）患者有脑膜炎，18例（7.5％）患有急性肾损伤。 12（5％）患者患有登革热和8（3.3％）的疟疾感染。结论：该研究表现出血液筛伤感染以及疾病过程以及对治疗的反应的广泛和变化呈现。诊断线索如发烧，ESCHAR，皮疹，淋巴结病，因为早期识别和治疗可以预防其危险并发症并降低由于疾病引起的死亡率。还应考虑到患者的更好管理，牢记有效的发生。

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