...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Clinical and Diagnostic Research >Comparison of Ocular Microbiome in Non-contact Lens and Contact Lens Users
【24h】

Comparison of Ocular Microbiome in Non-contact Lens and Contact Lens Users

机译：非隐形眼镜和隐形眼镜用户的眼部微生物组比较

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The resident/normal flora of conjunctiva is linked to infections of the eye in most cases in the wake of ocular surgery, trauma, implants in the eye or contact lens-related infections. Contact lenses due to their direct contact with the ocular surface exert shear stress, cause local trauma and thinning of the cornea. These factors may alter the ocular microbiome and hence may predispose the eye for corneal infiltrations and hence, infections.Aim: To analyse the normal conjunctival flora and compare the same with the microbiome of contact lens users.Materials and Methods: Two samples each from both the eye was collected from 40 non-contact lens users (n=80) and 40 daily contact lens users (n=80) from June 2018 to September 2018. The samples were inoculated onto blood agar, Mac Conkey agar and Sabourauda??s Dextrose Agar (SDA). Organisms were identified according to standard microbiological techniques. Antimicrobial susceptibility testing was done for Staphylococcus aureus and Gram-Negative Bacilli (GNB) isolates. The data obtained was in the form of percentages and were analysed using IBM SPSS statistics software version 25.0.Results: GNB including non-fermenter GNB, Pseudomonas, E.coli, Enterobacter cloacae, Citrobacter koseri, Proteus vulgaris, Klebsiella pneumoniae and Moraxella were isolated only from the conjunctiva of contact lens users and none from non-contact lens users (p-value <0.001). There were 12 GNB isolated from conjunctiva of contact lens users. Of them, 10 were ampicillin resistant, seven were amoxicillin-clavulanate resistant and three were cefotaxime resistant (p-value=0.012) but they were all sensitive to ceftriaxone, imipenem, levofloxacin, amikacin and ciprofloxacin.Conclusion: The use of contact lens significantly alters the normal conjunctival flora and are a potential source of infection. The present study helped in formulating antibiotic policy (prophylactic use and empiric treatment) for our healthcare establishment in both contact lens users and non-contact lens users.
机译：在眼科手术的外科术后，在大多数情况下，结膜的居民/正常植物群与眼睛的感染有关。眼睛或隐形眼镜相关的感染。由于它们直接接触到眼表面施加剪切应力，引起局部创伤和薄膜的隐形眼镜。这些因素可能改变眼部微生物组，因此可以使眼睛渗透和因此感染。目的：分析正常结膜菌群并与隐形眼镜用户的微生物组相比相同。材料和方法：从2018年6月到2018年6月，从40名非隐形眼镜用户（n = 80）和40个每日隐形眼镜用户（n = 80）中收集两种样品。将样品接种到血琼脂上，MAC巧克力琼脂和Sabourauda？S右旋糖琼脂（SDA）。根据标准微生物技术鉴定生物。对金黄色葡萄球菌和革兰氏阴性芽孢杆菌（GNB）分离株进行抗微生物易感性测试。所获得的数据以百分比的形式，使用IBM SPSS统计软件版本25.0分析。结果：GNB包括非发酵罐GNB，Pseudomonas，E.coli，Enterobacter Cloacae，Citrobacter Koseri，Protebacters，Klebsiella肺炎和肺炎Moraxella仅从隐形眼镜用户的结膜中分离，没有来自非隐形眼镜用户（P值<0.001）。从隐形眼镜用户的结膜中分离了12个GNB。其中10种是氨苄青霉素抗性，7种抗氨嘧啶 - 克拉维酸盐抗性，三个是头孢噻肟抗性（P值= 0.012），但它们对Ceftriaxone，Imipenem，左氧氟沙星，Amikacin和Ciprofloxacin敏感。结论：使用隐形眼镜显着改变正常的结膜菌群，是一种潜在的感染来源。本研究有助于在隐形眼镜用户和非隐形眼镜用户中为我们的医疗保健建立配制抗生素政策（预防性使用和经验处理）。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号