...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Clinical and Diagnostic Research >Fertility Potential of Microsurgical Subinguinal Varicocelectomy in Non-obstructive Azoospermia, Virtual Azoospermia and Severe Oligospermia Patients in a Tertiary Care Setup
【24h】

Fertility Potential of Microsurgical Subinguinal Varicocelectomy in Non-obstructive Azoospermia, Virtual Azoospermia and Severe Oligospermia Patients in a Tertiary Care Setup

机译：非阻塞性血吸虫，虚拟杂草症和严重少量蛋白患者的显微外科对讲术中显微外科对讲术中的生育能力

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The role of varicocelectomy in Non-Obstructive Azoospermia (NOA) and Severe Oligospermia (SO) remains controversial with some studies reporting improvement in these patients.Aim: To analyse the improvement in semen parameters and pregnancy outcomes after microsurgical varicocelectomy in NOA, SO and Virtual Azoospermia (VA) groups.Materials and Methods: A single centre six year prospective study, evaluating 25 adults with primary infertility having NOA, VA (<1 million/mL) or SO (1-5 million/mL) with clinical varicocele and normal female partner evaluation was conducted at a tertiary care centre. Microsurgical varicocelectomy along with needle aspiration biopsy of bilateral testes was done in all patients. Follow-up semen analysis was done at six monthsa?? postoperatively. The improvement in sperm count and sperm motility postoperatively was compared using Wilcoxon signed rank test and paired t-test respectively.Results: The mean age of patients were 31 years. There was significant overall improvement in both sperm count and progressive motility. Mean sperm count improved from 1.052 to 8.456 (million/mL) (mean improvement of 8.65 million/mL in VA group, and of 6.25 million/mL in SO group) while mean progressive motility improved from 15.76% to 24.4%. A total of 21 (84%) patients responded on follow-up. The non-respondersa?? group had two patients each from VA and SO groups. Pregnancy was achieved in five patients (20%), with spontaneous pregnancy in two and Intrauterine Insemination (IUI) in three patients. All patients with early maturation arrest were non-responders.Conclusion: Microsurgical subinguinal varicocelectomy can lead to significant increase in semen parameters in severe oligospermic men, which aids spontaneous or assisted pregnancy (IUI) in these couples. Hypospermatogenesis and late maturation arrest are favourable predictors of response after surgery.
机译：Varicocelectomy在非阻塞性血吸虫（NOA）和严重的寡核苷酸（SO）中的作用仍然存在于这些患者的一些研究进一步的研究。目的：分析NOA中显微外科瓦里奇切除术后精液参数和妊娠结果的改善，所以和虚拟Azoospermia（VA）组。材料和方法：单中心六年前瞻性研究，评价25名成人，含NOA，VA（<100万/ mL）左右（1-5百万/ mL） ）在第三节护理中心进行临床毒素和正常的女性伴侣评估。在所有患者中，在所有患者中都在双侧睾丸中与针吸入活检一起进行的显微外科瓦雷奇切除术。后续精液分析在六个月中完成？术后。比较术后术后术术患者患者患者患者的精子计数和精子运动的改善。结果：患者的平均年龄为31岁。精子数量和渐进式动力方面存在显着改善。平均精子计数从1.052增加到8.456（百万/ ml）（VA组中的平均改善为865万/ ml，同时为6.25亿/ ml），而平均渐进的动力从15.76％提高到24.4％。共有21例（84％）患者随访。非响应者??组有两名患者来自VA等群体。在三名患者中，在五名患者（20％）中患者（20％）达到怀孕，在三名患者中有两种和宫内授精（IUI）。所有早熟逮捕的患者都是非反应者。结论：显微外科亚语静脉曲张切除术可导致严重寡核苷酸中的精液参数显着增加，这有助于这些夫妻中的自发性或辅助妊娠（IUI）。软疗法和晚期成熟逮捕是手术后反应的有利预测因子。

著录项

相似文献

  • 外文文献
  • 中文文献
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号