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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Fournier’s Gangrene: A Study of 14 Cases
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Fournier’s Gangrene: A Study of 14 Cases

机译：Fournier的Gangrene：一项研究14例

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Fournier’s Gangrene (FG) is a life-threatening form of infective necrotising fasciitis affecting the genital, perineal or perianal regions. Men are mostly affected though women and children may also be affected. Despite aggressive treatment, the mortality rate of FG remains high.Aim: To study demographic pattern of FG, its predisposing factors and aetiological agents, locations of infective gangrene and outcomes of treatment in a geographical area.Materials and Methods: This retrospective study included data of 14 patients of FG admitted to the surgical units of the Institute with FG, between July 2017 to June 2019, which were analysed. The commonly affected sites, predisposing factors, causative organisms, and outcomes of management of FG were studied.Results: All the 14 patients were males; their mean age was 54.57 years (28-75 years). The mean duration from the onset of symptoms to admission to the hospital was 6.7 days (2-11 days). The mean hospitalisation time was 22.6 days (2-35 days). Six (42.86%) and 3 (21.43%) patients had FG secondary to perianal and scrotal infections respectively. Diabetes mellitus as a predisposing factor was found in 9 (64.29%) patients. There was no definite predisposing or co-morbid condition in 3 (21.43%) patients. The most frequent bacterial organism was Escherichia coli in 11 (78.57%) patients. The overall mortality was 5 (35.71%) out of the 14 patients. Mortality was highest in patients presenting with sepsis and diabetes mellitus.Conclusion: FG is a rapidly progressive, fulminant infection. In spite of aggressive surgical approach and broad spectrum antimicrobial combinations, the prognosis remains grave especially when it is associated with diabetes mellitus and sepsis.
机译：Fournier的Gangrene（FG）是一种危及生命的坏同性筋膜炎的危及生命形式，影响生殖器，会阴或肛周区域。虽然妇女和儿童也可能受到影响，但男人大多受到影响。尽管有激进的治疗，但FG的死亡率仍然很高。目的：研究FG的人口统计模式，其概述因素和治疗剂，感染性坏疽的位置和地理区域治疗的结果。材料和方法：这项回顾性研究包括2017年7月至2019年6月至2019年6月，截至2019年6月至2019年6月，截至2019年6月的14名FG患者的数据。研究了常见影响的遗址，易受造成的因素，致病生物和FG管理结果。结果：所有14名患者都是男性;他们的平均年龄为54.57岁（28-75岁）。从症状开始入院的平均持续时间为6.7天（2-11天）。平均住院时间为22.6天（2-35天）。六（42.86％）和3名（21.43％）患者分别具有FG继发于肛周和阴囊感染。糖尿病作为易感因子被发现在9例（64.29％）患者中发现。 3（21.43％）患者中没有明确的预感或共同病态。最常见的细菌生物是11（78.57％）患者的大肠杆菌。 14名患者中，总死亡率为5（35.71％）。患有败血症和糖尿病患者的患者中死亡率最高。结论：FG是一种迅速进行的，令人震撼的感染。尽管有激进的手术方法和广泛的谱抗微生物组合，但预后仍然严重，特别是当它与糖尿病和败血症有关时。

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