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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Cervical Cytological Changes Associated with Prolonged Sexual Exposure due to Early Marriage in Rural India
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Cervical Cytological Changes Associated with Prolonged Sexual Exposure due to Early Marriage in Rural India

机译：由于印度农村早婚，宫颈细胞学变化与长期性暴露相关

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There is likelihood of development of premalignant changes in the cervix in the teenagers due to early sexual activity. This assumes importance under rural conditions in India where majority of marriage of girls are performed at young age below 20 years.Aim: The present cytological study was carried out in the three cohorts of rural girls- adolescents (16-20 years), young adult girls (21-25 years) and adult women (26-30 years) to see the effect of early increasing sexual exposure.Materials and Methods: The study cases were derived from the cervical cancer screening which is in progress in the rural population of Lucknow, Uttar Pradesh, India. Of the 1185 study cases, 97 were adolescents, 338 young adult girls and remaining 750 were adult women.Results: The Atypical Squamous Cell Changes of Unknown Significance (ASCUS) were found higher in the adolescents than in young adult girls and adult women while Squamous Intraepithelial Lesions of cervix (SIL) rate was almost equal in the three cohorts. Follow-up revealed progression of ASCUS to Low grade SIL (LSIL) almost equal in the three groups while the persistence of SIL was higher in the young adult girls and adult women. The gynaecological symptoms especially vaginal discharge was more common in the last two groups than in adolescents but the SIL rate was higher with all symptoms in the adolescents. The cervical lesions were more common in the young girls and adult women and SIL rate was higher with different cervical lesions. The majority of adolescents were nulliparous with high SIL rate while in the young adult girls and adult women, the SIL incidence showed rising trend with increasing parity.Conclusion: The study highlights the importance of cytological screening of all the rural young girls and adult women specially who reveal cervical lesions or are symptomatic. This will yield large number of pre-cancerous cases, timely treatment of which will check the progression of SIL to malignancy.
机译：由于早期性活动，青少年中子宫内宫颈发生的可能性的可能性。这假设在印度的农村条件下的重要性，女孩的大多数女孩在20年后的年轻时进行。目的：目前的细胞学研究是在农村女孩 - 青少年（16 - 20年）的三个队列中进行了，年轻的成年女孩（21-25岁）和成年女性（26-30岁）看到早期增加性暴露的效果。材料和方法：研究病例来自正在进行的宫颈癌筛查在勒克瑙人口，北方邦，印度。在1185名研究病例中，97名是青少年，338名年轻成人女孩和剩下的750名成年女性。结果：青少年在青少年中发现了不明显的意义（Ascus）的非典型鳞状细胞变化比年轻成人女孩和成人更高女性在三个队列中鳞状上皮内病变率几乎相等。随访揭示了ASCUS到低级SIL（LSIL）的进展在三组中几乎相等，而SIL的持久性在年轻的成年女孩和成年女性中较高。妇科症状尤其是阴道分泌物在过去两组中比在青少年中更常见，但在青少年的所有症状中，SIL率较高。宫颈病变在年轻女孩和成年女性中更常见，患有不同宫颈病变的SIL率较高。大多数青少年在年轻的成年女性和成年女性中都有高的SIL率，SIL发病率随着额远增加趋势而呈上升趋势。结论：该研究突出了整个农村年轻女孩的细胞学筛选的重要性特殊的成年女性揭示宫颈病变或症状。这将产生大量的癌症案例，及时治疗，这将检查SIL的进展至恶性肿瘤。

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