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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Seroprevalence and Trend of Hepatitis B and C Viral Infections in Patients at a Tertiary Care Hospital in Southern India- A Retrospective Study
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Seroprevalence and Trend of Hepatitis B and C Viral Infections in Patients at a Tertiary Care Hospital in Southern India- A Retrospective Study

机译：印度南部三级护理医院患者乙型肝炎和C病毒感染的血清升迁与趋势 - 回顾性研究

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Hepatitis B Virus (HBV) and Hepatitis C Virus (HCV) are serious public health problems worldwide with estimated 350 million chronically infected people. Transmission of infection occurs through blood transfusion, needles, body fluids and sexual intercourse. To know the magnitude of transmission of any disease in a community and for its control and prevention; trend and study of its prevalence is most important.Aim: To analyse the overall trend of HBV and HCV infection and to estimate the seroprevalence in a tertiary care hospital of Southern India.Materials and Methods: This was a retrospective study conducted at the Department of Microbiology, Sri Venkateswara Institute of Medical Sciences (SVIMS), Tirupati, Andhra Pradesh, India. The data of 77,158 and 58,024 samples for the test of Hepatitis B surface antigen (HBsAg) and test for anti-hepatitis C antibody respectively, for a period of three years four months (from September 2013 to December 2016) was retrieved from Departmental registers and Hospital Information System. Statistical software IBM SPSS, Version 20.0 (IBM SPSS Statistic, Somers NY, USA) was used for statistical analysis.Results: A total of 77,158 samples were tested for HBsAg whereas, 58,024 were tested for the presence of anti-HCV antibody. Seroprevalence of HBV was 2.27% and for HCV, it was 0.73%.Conclusion: HBV infection is showing a decreasing trend and the HCV infection, a fluctuating trend. Attempt should be made to reduce the incidence of HBV and HCV by simple preventive measures like public education, screening of blood and blood products, increasing public awareness about importance of vaccination.
机译：乙型肝炎病毒（HBV）和丙型肝炎病毒（HCV）是全世界严重的公共卫生问题，估计3.5亿令人慢性受感染的人。感染的传播通过输血，针，体液和性交发生。了解社区中任何疾病的传播程度，并进行控制和预防;对其流行率的趋势和研究是最重要的。目的：分析HBV和HCV感染的总体趋势，并估算印度南部第三节护理医院的塞开修机。材料与方法：这是回顾性研究在Microbiology系，SRI Venkateswara医学科学研究所（SVIMS），Tirupati，Andhra Pradesh，印度。 77,158和58,024个样品的数据用于乙型肝炎表面抗原（HBsAg）和抗丙型肝炎抗体的测试，分别为期三年（2013年9月至2016年9月），从部门登记服务中检索医院信息系统。统计软件IBM SPSS，版本20.0（IBM SPSS统计信息，Somers Ny，USA）用于统计分析。结果：对HBsAg进行了总共测试了77,158个样品，而抗HCV抗体的存在测试58,024个样品。 HBV的Seroprengally为2.27％，对于HCV为0.73％。结论：HBV感染呈现趋势和HCV感染，波动趋势。通过简单的预防措施，如公共教育，血液和血液产品的筛查，应促进HBV和HCV的发生率，提高公众对疫苗接种重要性的认识。

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