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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Unidentical Double Trouble- A Rare Case Report
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Unidentical Double Trouble- A Rare Case Report

机译：直立双重麻烦 - 稀有案例报告

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Collision tumours are relatively rare entities and are thus, not well recognised. Collision tumour can be defined as two coexisting but histologically different malignancies involving the same organ or adjacent organ with an equivocal intermediate transitional zone between them. Collision tumours of the lung and oesophagus are very rare. Such cases are diagnosed by Computerised Tomogram (CT) Scan or Chest X-Ray for complaint of dysphagia. Definitive diagnosis is made by tissue biopsy. Here, a 66-year-old male is admitted for evaluation of an anterior mediastinal mass. Radiology revealed an anterior mediastinal mass extending in to the left hilar region and upper lobe of right lung anteriorly and in to the lower end of oesophagus posteriorly. Biopsy was performed. Microscopically, transbronchial biopsy revealed a cellular lesion, composed of round-to-oval cells with streaming nucleus, positive for Immunohistochemistry (IHC) markers, CD-56 and Synaptophysin pertaining to a diagnosis of small cell carcinoma. Biopsy of the oesophageal growth shows nest of dysplastic squamous epithelium which infiltrates into underlying muscularis propria showing features of a squamous cell carcinoma. Multiple fragments of squamous epithelium are also seen with necrotic tissue in vicinity and acute inflammatory exudate. Few cells show multinucleation, molding and margination of chromatin, showing the characteristic morphological features of Herpes oesophagitis. The patient was administered platinum-based Chemotherpy.
机译：碰撞肿瘤是相对罕见的实体，因此不公认。碰撞肿瘤可以定义为两个共存但组织学上不同的恶性肿瘤，涉及相同的器官或邻近器官，其中含有各种反圆周的中间过渡带。肺和食道的碰撞肿瘤非常罕见。这种情况被通过计算机化图像（CT）扫描或胸部X射线诊断为困扰吞咽困难。明确的诊断是由组织活组织检查进行的。在这里，一名66岁的男性被录取评估前纵隔物质。放射学揭示了前纵隔的前纵隔物体向后延伸到左侧肺部的左侧肺部和上部叶，并在前的食道下端。进行活组织检查。显微镜，跨晶体活检显示细胞病变，由圆形到椭圆形细胞组成，具有流核，免疫组织化学（IHC）标记，CD-56和突触菌属，属于小细胞癌的诊断。食管生长的活检显示出消化性鳞状上皮的巢，其渗透到潜在的肌肉脑血栓，显示鳞状细胞癌的特征。在附近的坏死组织和急性炎症渗出物的坏死组织也看到多个鳞状上皮碎片。少量细胞显示染色质的多核，模塑和游击，显示出疱疹性疱疹性的特征形态特征。患者被施用铂基化学检。

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