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首页> 外文期刊>Scientific reports. >Incidence and risk factors of acute kidney injury in critically ill patients from a single centre in Brazil: a retrospective cohort analysis
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Incidence and risk factors of acute kidney injury in critically ill patients from a single centre in Brazil: a retrospective cohort analysis

机译：巴西单一中心患者急性肾损伤的发病率及危险因素：回顾性队列队列分析

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Studies with a comprehensive analysis of the epidemiology of acute kidney injury (AKI) in intensive care units (ICUs) are still limited in developing countries. The aim of this study is to identify the incidence and risk factors of AKI in critically ill patients from a Brazilian ICU. We performed a retrospective analysis of the records of patients admitted to a single-centre adult ICU in Brazil between 1 January 2011 and 31 December 2016. The KDIGO criteria were used to define AKI. Univariate and multivariate data analyses were carried out. We included 1,500 patients. The incidence of AKI was 40.5%, and the AKI dialysis rate was 13%. The predictors of AKI at ICU admission included hypertension [odds ratio (OR)?=?1.44, p 0.017], high serum creatinine concentration [OR?=?3.54; p??0.001], low serum albumin concentration [OR?=?1.42, p 0.015], high APACHE II score [OR?=?2.10; p??0.001] and high SAPS 3 [OR?=?1.75; p??0.001]. The incidence of AKI was high, and we identified the predictors of AKI among critically ill Brazilian patients. The results of this study may contribute to the implementation of targeted therapies.
机译：全面分析了强化护理单位（ICU）的急性肾损伤（AKI）流行病学的研究仍然有限。本研究的目的是识别来自巴西ICU的危重病患者Aki的发病率和危险因素。我们对2011年1月1日至2016年12月31日在巴西入住的患者记录的回顾性分析。KDIGO标准用于定义AKI。进行单变量和多变量数据分析。我们包括1,500名患者。 AKI的发病率为40.5％，AKI透析率为13％。 ICU入院AKI的预测因子包括高血压[差距（或）？=？1.44，P 0.017]，高血清肌酐浓度[或α= 3.54; p？<〜0.001]，低血清白蛋白浓度[或α=Δ1.42，p 0.015]，高apache II得分[或？=？2.10; p？<？0.001]和高分子3 [或？=？1.75; p？<？0.001]。 AKI的发病率很高，我们确定了批判性的巴西患者中AKI的预测因素。本研究的结果可能有助于实施有针对性的疗法。

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