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Impact of Metabolic Syndrome Components in High-Risk Cardiovascular Disease Development in Older Adults

机译:代谢综合征成分在老年人高危心血管疾病发育中的影响

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Objective: Analyze the influence between the components of metabolic syndrome and the independent risk for cardiovascular disease (CVD) in the elderly. Methods: A descriptive cross-sectional study was carried out with 205 older adults from a primary healthcare unit of the Federal District, Brazil. The cardiovascular risk was determined by the Framingham Risk Score (FRS). The National Cholesterol Evaluation Program for Adult Treatment Panel III 2001 (NCEP-ATP III) criteria were considered to analyze metabolic syndrome (MS) diagnoses. Results: There was a strong association between MS and high cardiovascular risk (OR = 8.86). The univariate analysis main findings revealed that male gender, diabetes, smoking habit, systolic blood pressure, HDL level, high blood glucose, glycated hemoglobin, and LDL level were associated with high cardiovascular risk. FRS increases significantly with the presence of four or more MS components (by 30%, if 4 components are present, and by 40%, if 5 components) when compared with the presence of three or fewer components (P 0.001). A logistic regression analysis of high-risk predictors was described to reduce the effects of confounding and bias factors. Conclusion: The identification of MS associated with high FRS values represents a cascading of adverse effects on the population’s aging process.
机译:目的:分析老年人代谢综合征组分与心血管疾病(CVD)的独立风险的影响。方法:采用巴西联邦区的主要医疗单位的205名老年人进行了描述性横截面研究。心血管风险由Framingham风险分数(FRS)确定。将成人治疗专家组III 2001(NCEP-ATP III)标准的国家胆固醇评估计划进行了考虑分析代谢综合征(MS)诊断。结果:MS与高心血管风险之间存在强烈关联(或= 8.86)。单变量分析主要研究结果显示,男性性别,糖尿病,吸烟习惯,收缩压,HDL水平,高血糖,糖化血红蛋白和LDL水平与高心血管风险有关。与存在三个或更少组分的存在相比,FRS在存在四个或更多个MS组分(如果存在4个组分,如果存在4个组分,则达到40%,如果5个组分),则FRS会显着增加。描述了高风险预测因子的逻辑回归分析,以减少混淆和偏置因素的影响。结论:与高FRS值相关的MS的鉴定代表了对人口老化过程的不利影响的级联。
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