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Incidence, prevalence, and mortality of heart failure: a nationwide registry study from 2013 to 2016

机译:心力衰竭的发病,患病率和死亡率:2013年至2016年全国注册表研究

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Aims Large‐scaled population studies of incidence and prevalence of heart failure (HF) are needed for the development of healthcare policies and priorities. The aim of this study was to estimate the incidence, prevalence, and all‐cause mortality of HF in Norway from 2013 to 2016 on the basis of a national registry. Methods and results Using data from the nationwide Norwegian Prescription Database, we identified all patients ≥18?years of age in Norway with at least one drug prescription with HF during 2013–2016, defined by 10th revision of the International Classification of Diseases (ICD‐10) codes I50, I11, I13, or I42. The individual index date was the date of the first prescription. Patients were followed up until death or end of follow‐up (31 October 2017). Annual incidence and prevalence were estimated from 2013 to 2016, using a look‐back period starting from 1 March 2008. We calculated standardized estimates by applying direct age and sex standardization to the 2013 European standard population. All‐cause mortality from 2013 to 2016 was calculated among the prevalent HF patients. Standardized mortality ratio (SMR) was calculated by indirect standardization using general mortality in the Norwegian population as reference. We identified 54?542 unique patients (58% men) with a first‐time diagnosis of HF. The median age was 72?±14?years, and women were older than men (median age 76 vs. 70?years, respectively). The crude (standardized) incidence of HF was 3.44/1000 (4.23/1000) person‐years in 2016 and did not increase over the 4?year period, while the prevalence increased from 2.0% (2.3%) to 2.4% (2.8%). Both incidence and prevalence were higher in men than in women and strongly associated with age. Crude mortality rates in the HF population declined from 94 to 82/1000 person‐years from 2013 to 2016, and SMR declined from 2.01 to 1.84. Age‐adjusted mortality rates were higher in men than in women. Conclusions This nationwide registry study in Norway showed an increase in the prevalence of HF from 2013 to 2016, with stable incidence rates and improved survival.
机译:旨在制定医疗保健政策和优先事项所需的大规模人口对心力衰竭的发病率和患病率(HF)。本研究的目的是估算2013年至2016年挪威的发病率,患病率和全面死亡率,从2013年到2016年在国家登记处。使用全国挪威处方数据库的数据的方法和结果,我们鉴定了挪威的所有患者≥18岁,在2013 - 2016年期间至少有一个药物处方,由第10次修订国际疾病分类(ICD- 10)代码I50,I11,I13或I42。个人指数日期是第一个处方的日期。患者随访,直到死亡或后续结束(2017年10月31日)。从2008年3月1日起,使用了从2013年到2016年估计了年度发病率和患病率。我们通过向2013年欧洲标准人口应用直率和性标准化来计算标准化估计。从2013年至2016年开始,普遍存在的HF患者的全因死亡率。标准化死亡率(SMR)是通过在挪威人群中的一般死亡率作为参考的间接标准化计算的。我们鉴定了54名独特的患者(58%的男性),首次诊断HF。中位年龄为72岁?±14岁?岁月比男性年龄大(中位数76岁,分别为70岁)。 HF的原油(标准化)发病率为2016年的3.44 / 1000(4.23 / 1000),但在4年期间没有增加,患病率从2.0%增加到2.4%(2.8%) )。男性发病率和患病率均高于女性和与年龄的强烈相关。 HF人口中的原油死亡率从2013年到2016年的94人到82/1000人,SMR从2.01到1.84下降。男性年龄调整的死亡率比女性更高。结论挪威的全国注册表研究表明,2013年至2016年的HF普遍性增加,发病率稳定,生存稳定。

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